Browsing by Author "Siveen, Kodappully S"
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The Role of Extracellular Vesicles as Modulators of the Tumor Microenvironment, Metastasis and Drug Resistance in Colorectal Cancer.
Siveen, Kodappully S; Raza, Afsheen; Ahmed, Eiman I; Khan, Abdul Q; Prabhu, Kirti S; Kuttikrishnan, Shilpa; Mateo, Jericha M; Zayed, Hatem; Rasul, Kakil; Azizi, Fouad; Dermime, Said; Steinhoff, Martin; Uddin, Shahab... more authors ... less authors ( MDPI , 2019 , Article)Colorectal cancer (CRC) is one of the most common cancers worldwide, with high morbidity and mortality rates. A number of factors including modulation of the tumor microenvironment, high metastatic capability, and resistance ... -
Sanguinarine Induces Apoptosis in Papillary Thyroid Cancer Cells via Generation of Reactive Oxygen Species.
Khan, Abdul Q; Mohamed, Elham A N; Hakeem, Ishrat; Nazeer, Aneeza; Kuttikrishnan, Shilpa; Prabhu, Kirti S; Siveen, Kodappully S; Nawaz, Zafar; Ahmad, Aamir; Zayed, Hatem; Uddin, Shahab... more authors ... less authors ( MDPI , 2020 , Article)Sanguinarine (SNG), a natural compound with an array of pharmacological activities, has promising therapeutic potential against a number of pathological conditions, including malignancies. In the present study, we have ... -
Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling.
Akhtar, Sabah; Achkar, Iman W; Siveen, Kodappully S; Kuttikrishnan, Shilpa; Prabhu, Kirti S; Khan, Abdul Q; Ahmed, Eiman I; Sahir, Fairooz; Jerobin, Jayakumar; Raza, Afsheen; Merhi, Maysaloun; Elsabah, Hesham M; Taha, Ruba; Omri, Halima El; Zayed, Hatem; Dermime, Said; Steinhoff, Martin; Uddin, Shahab... more authors ... less authors ( Frontiers Media , 2019 , Article)Sanguinarine (SNG), a benzophenanthridine alkaloid, has displayed various anticancer abilities in several vivo and studies. However, the anticancer potential of SNG is yet to be established in multiple myeloma (MM), a ... -
Sanguinarine mediated anti-tumor activity via targeting JAK/STAT3 pathway in thyroid cancer
Ahmed, Elham; Khan, Abdul; S.Prabhu, Kirti; Siveen, Kodappully; Nawaz, Zafar; Zayed, Hatem; Uddin, Shahab... more authors ... less authors ( Qatar University Press , 2020 , Poster)Sanguinarine (SNG), a natural compound with an array of pharmacological activities, has promising therapeutic potential against a number of pathological conditions, including malignancies. This research aimed to investigate ...