• Adding colchicine to tocilizumab in hospitalized patients with severe COVID-19 pneumonia: An open-label randomized controlled trial 

      Rahhal, Alaa; Najim, Mostafa; Aljundi, Amer Hussein; Mahfouz, Ahmed; Alyafei, Sumaya Mehdar; ... more authors ( Lippincott Williams and Wilkins , 2022 , Article)
      Introduction: Colchicine acts upstream in the cytokines cascade by inhibiting the nod-like receptor protein 3 (NLRP3) inflammasome while interleukin 6 (IL-6) receptor antagonists, such as tocilizumab, block the end result ...