Browsing by Author "Naja, Khaled"
Now showing items 1-4 of 4
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Association between antioxidant metabolites and N-terminal fragment brain natriuretic peptides in insulin-resistant individuals.
( Lippincott, Williams & Wilkins , 2024 , Article)Oxidative stress plays a pivotal role in the development of metabolic syndrome, including heart failure and insulin resistance. The N-terminal fragment of brain natriuretic peptide (NT-proBNP) has been associated with ... -
Metformin increases 3-hydroxy medium chain fatty acids in patients with type 2 diabetes: a cross-sectional pharmacometabolomic study
( Frontiers Media SA , 2024 , Article)Background: Metformin is a drug with a long history of providing benefits in diabetes management and beyond. The mechanisms of action of metformin are complex, and continue to be actively debated and investigated. The aim ... -
Pharmacometabolomics of sulfonylureas in patients with type 2 diabetes: a cross-sectional study
( Frontiers Media SA , 2024 , Article)Background: Sulfonylureas have been a longstanding pharmacotherapy in the management of type 2 diabetes, with potential benefits beyond glycemic control. Although sulfonylureas are effective, interindividual variability ... -
Targeted Inhibition of GATA-3 by Pyrrothiogatain: Implications for Adipocyte Biology and Inflammatory Response
( Multidisciplinary Digital Publishing Institute (MDPI) , 2025 , Article)GATA-3 is a master regulator of preadipocyte differentiation and function. Pharmacological or genetic targeting of GATA-3 will allow us to understand the function of GATA-3 in regulating metabolism, insulin signaling, and ...
