• English
    • العربية
  • العربية
  • Login
  • QU
  • QU Library
  •  Home
  • Communities & Collections
Browsing by Author 
  •   Qatar University Digital Hub
  • Browsing by Author
  • Qatar University Digital Hub
  • Browsing by Author
  •      
  •  
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browsing by Author "Lai, F. Anthony"

    • 0-9
    • A
    • B
    • C
    • D
    • E
    • F
    • G
    • H
    • I
    • J
    • K
    • L
    • M
    • N
    • O
    • P
    • Q
    • R
    • S
    • T
    • U
    • V
    • W
    • X
    • Y
    • Z

    Sort by:

    Order:

    Results:

    Now showing items 1-6 of 6

    • title
    • publication date
    • submit date
    • ascending
    • descending
    • 5
    • 10
    • 20
    • 40
    • 60
    • 80
    • 100
      • Thumbnail

        Antigen Unmasking Is Required to Clinically Assess Levels and Localisation Patterns of Phospholipase C Zeta in Human Sperm 

        Kashir, Junaid; Mistry, Bhavesh V.; BuSaleh, Lujain; Nomikos, Michail; Almuqayyil, Sarah; Abu-Dawud, Raed; AlYacoub, Nadya; Hamdan, Hamdan; AlHassan, Saad; Lai, F. Anthony; Assiri, Abdullah M.; Coskun, Serdar... more authors ... less authors ( MDPI , 2023 , Article)
        Mammalian oocyte activation is initiated by intracellular calcium (Ca2+) oscillations, driven by the testis-specific phospholipase C zeta (PLCζ). Sperm PLCζ analysis represents a diagnostic measure of sperm fertilisation ...
      • Thumbnail

        Arrhythmia-Associated Calmodulin E105A Mutation Alters the Binding Affinity of CaM to a Ryanodine Receptor 2 CaM-Binding Pocket 

        Thanassoulas, Angelos; Theodoridou, Maria; Barrak, Laila; Riguene, Emna; Alyaarabi, Tamader; Elrayess, Mohamed A.; Lai, F. Anthony; Nomikos, Michail... more authors ... less authors ( MDPI , 2023 , Article)
        Calmodulin (CaM) is a small, multifunctional calcium (Ca2+)-binding sensor that binds and regulates the open probability of cardiac ryanodine receptor 2 (RyR2) at both low and high cytosolic Ca2+ concentrations. Recent ...
      • Thumbnail

        Divergent Biochemical Properties and Disparate Impact of Arrhythmogenic Calmodulin Mutations on Zebrafish Cardiac Function 

        Da'as, Sahar I.; Thanassoulas, Angelos; Calver, Brian L.; Saleh, Alaaeldin; Abdelrahman, Doua; Hasan, Waseem; Safieh-Garabedian, Bared; Kontogianni, Iris; Nasrallah, Gheyath K.; Nounesis, George; Lai, F. Anthony; Nomikos, Michail... more authors ... less authors ( John Wiley & Sons , 2024 , Article)
        Calmodulin (CaM) is a ubiquitous, small cytosolic calcium (Ca2+)-binding sensor that plays a vital role in many cellular processes by binding and regulating the activity of over 300 protein targets. In cardiac muscle, CaM ...
      • Thumbnail

        Editorial: The role of calcium signaling in gametogenesis and early embryogenesis 

        Kashir, Junaid; Lai, F. Anthony; Nomikos, Michail ( Frontiers Media , 2022 , Article)
        Calcium homeostasis exerts a profound role in determining the quality of gametogenesis, the resultant efficacy of fertilisation and ultimately the competency of embryogenesis. Perhaps no other single ion plays such a ...
      • Thumbnail

        Life-threatening arrhythmogenic CaM mutations disrupt CaM binding to a distinct RyR2 CaM-binding pocket 

        Angelos, Thanassoulas; Vassilakopoulou, Vyronia; Calver, Brian L.; Buntwal, Luke; Smith, Adrian; Lai, Christopher; Kontogianni, Iris; Livaniou, Evangelia; Nounesis, George; Lai, F. Anthony; Nomikos, Michail... more authors ... less authors ( Elsevier , 2023 , Article)
        Calmodulin (CaM) modulates the activity of several proteins that play a key role in excitation-contraction coupling (ECC). In cardiac muscle, the major binding partner of CaM is the type-2 ryanodine receptor (RyR2) and ...
      • Thumbnail

        SPERM FACTORS AND EGG ACTIVATION The structure and function relationship of sperm PLCZ1 

        Thanassoulas, Angelos; Swann, Karl; Lai, F. Anthony; Nomikos, Michail ( BioScientifica , 2022 , Article Review)
        In 2002, sperm-specific phospholipase C zeta1 (PLCZ1) was discovered and through these 20 years, it has been established as the predominant sperm oocyte-activating factor. PLCZ1 cRNA expression or direct protein microinjection ...

        Qatar University Digital Hub is a digital collection operated and maintained by the Qatar University Library and supported by the ITS department

        Contact Us | Send Feedback
        Contact Us | Send Feedback | QU

         

         

        Home

        Submit your QU affiliated work

        Browse

        All of Digital Hub
          Communities & Collections Publication Date Author Title Subject Type Language Publisher

        My Account

        Login

        Qatar University Digital Hub is a digital collection operated and maintained by the Qatar University Library and supported by the ITS department

        Contact Us | Send Feedback
        Contact Us | Send Feedback | QU