تصفح حسب المؤلف "Elsayegh, Dina"
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Early Hepatic Gene Expression Profile of Lipid Metabolism of Mice on High Fat Diet after Treatment with Anti‐Obesity Drugs
Rizk, Nasser M; Saleh, Amena; Elsayegh, Dina; Algamal, Abdelrahman ( FASEB , 2020 , Conference Paper)Obesity is a multifactorial disorder of global scale. The liver plays a vital role in fat metabolism. Disorder of hepatic fat metabolism is associated with obesity and fatty liver disease. This study aimed to detect the ... -
The Expression of TBC1 Domain Family, Member 4 (TBC1D4) in Skeletal Muscles of Insulin-Resistant Mice in Response to Sulforaphane
Rizk, Nasser M; ElGamal, Abdelrahman; Elsayegh, Dina; Cakir, Isin; Ghamari-Langroudi, Masoud ( Endocrine Society , 2020 , Conference Paper)The Expression of TBC1 Domain Family, member 4 (TBC1D4) in Skeletal Muscles of Insulin-Resistant Mice in Response to Sulforaphane. Background: Obesity is commonly accompanied by impaired glucose homeostasis. Decreased ... -
PROFILE OF OXIDATIVE STRESS GENES IN RESPONSE TO OBESITY TREATMENT
AHMED, AMIRA; FARAH, HUDA; Ahmed, Omnia; Elsayegh, Dina; ElGamal, Abdelrahman; Rizk, Nasser Moustafa... more authors ... less authors ( Qatar University Press , 2021 , Poster)Background: Oxidative stress (OS) is an imbalance between free radical production and the antioxidants defense in the body. Previous studies demonstrated the correlation of OS to the increased risk of developing metabolic ... -
Sulforaphane Downregulates Hepatic Fibroblast Growth Factor 21 (FGF21) of Diet Induced Obese Mice
Rizk, Nasser; Noureldin, Arwa; Galal, Aya; Mohamed, Omnia; ElGamal, Abdelrahman; Elsayegh, Dina... more authors ... less authors ( The Obesity Society , 2020 , Conference Paper)Background: Fibroblast growth factor 21 is a hormone-like protein that plays a critical role as an energy regulator. Sulforaphane (SFN) is expected to have potential therapeutic effects in treating obesity. This study aims ... -
Sulforaphane reduces obesity by reversing leptin resistance.
Çakır, Işın; Lining Pan, Pauline; Hadley, Colleen K; El-Gamal, Abdulrahman; Fadel, Amina; Elsayegh, Dina; Mohamed, Omnia; Rizk, Nasser M; Ghamari-Langroudi, Masoud... more authors ... less authors ( eLife Sciences Publications , 2022 , Article)The ascending prevalence of obesity in recent decades is commonly associated with soaring morbidity and mortality rates, resulting in increased health-care costs and decreased quality of life. A systemic state of stress ...