Browsing by Author "Cavallari, Larisa"
Now showing items 1-4 of 4
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Effect of CYP2C19 genetic variants on bleeding and major adverse cardiovascular events in a cohort of Arab patients undergoing percutaneous coronary intervention and stent implantation
( Lippincott Williams and Wilkins , 2022 , Article)Introduction One-third of patients have clopidogrel resistance that may lead to major adverse cardiac events (MACEs). By contrast, it was found that some clopidogrel-treated patients have hyperresponsive platelets that are ... -
The effect of genetic and nongenetic factors on warfarin dose variability in Qatari population.
( Pharmacogenomics Journal , 2020 , Article)The objective of this study is to estimate the prevalence of VKORC1, CYP2C9, and CYP4F2 genetic variants and their contribution to warfarin dose variability in Qataris. One hundred and fifty warfarin-treated Qatari patients ... -
Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study
( Elsevier , 2013 , Article)Summary BackgroundVKORC1 and CYP2C9 are important contributors to warfarin dose variability, but explain less variability for individuals of African descent than for those of European or Asian descent. We aimed to identify ... -
Periprocedural Anticoagulation Management of Patients receiving Warfarin in Qatar: A Prospective Cohort Study
( Elsevier , 2021 , Article)Background: The use of anticoagulant bridging remains controversial. This study was conducted to evaluate our warfarin periprocedural management in Qatar and investigate the associated clinical outcomes with such management. ...
