Browsing by Author "Ghanem, Simona S"
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Novel engineered nanobodies specific for N-terminal region of alpha-synuclein recognize Lewy-body pathology and inhibit in-vitro seeded aggregation and toxicity.
Hmila, Issam; Vaikath, Nishant N; Majbour, Nour K; Erskine, Daniel; Sudhakaran, Indulekha P; Gupta, Vijay; Ghanem, Simona S; Islam, Zeyaul; Emara, Mohamed M; Abdesselem, Houari B; Kolatkar, Prasanna R; Achappa, Devaya K; Vinardell, Tatiana; El-Agnaf, Omar M A... more authors ... less authors ( FEBS PRESS , 2022 , Article)Nanobodies (Nbs), the single-domain antigen-binding fragments of dromedary heavy-chain antibodies (HCAb), are excellent candidates as therapeutic and diagnostic tools in synucleinopathies because of their small size, ...