Browsing by Author "Parenti, Astrid"
Now showing items 1-4 of 4
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Dexamethasone induces the expression and function of tryptophan-2-3-dioxygenase in sk-mel-28 melanoma cells
Cecchi, Marta; Paccosi, Sara; Silvano, Angela; Eid, Ali Hussein; Parenti, Astrid ( MDPI , 2021 , Article)Tryptophan-2,3-dioxygenase (TDO) is one of the key tryptophan-catabolizing enzymes with immunoregulatory properties in cancer. Contrary to expectation, clinical trials showed that inhibitors of the ubiquitously expressed ... -
Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells via Tryptophan 2,3 Dioxygenase
Cecchi, Marta; Mannini, Antonella; Lapucci, Andrea; Silvano, Angela; Lulli, Matteo; Luceri, Cristina; D’Ambrosio, Mario; Chiarugi, Alberto; Eid, Ali H.; Parenti, Astrid... more authors ... less authors ( Frontiers Media , 2022 , Article)In addition to its well-established immunosuppressive actions, tryptophan 2,3-dioxygenase (TDO) appears to elicit direct effects on tumor cell function. Although TDO has been associated with cancer stemness, its involvement ... -
Oxidative Stress-Induced Endothelial Dysfunction in Cardiovascular Diseases
Shaito, Abdullah; Aramouni, Karl; Assaf, Roland; Parenti, Astrid; Orekhov, Alexander; El Yazbi, Ahmed; Pintus, Gianfranco; Eid, Ali H.... more authors ... less authors ( IMR Press , 2022 , Article Review)Cardiovascular disease (CVD) is a major cause of mortality worldwide. A better understanding of the mechanisms underlying CVD is key for better management or prevention. Oxidative stress has been strongly implicated in the ... -
Vascular inflammation: Players and modulators
Eid, Ali H.; Parenti, Astrid ( Bentham Science Publishers , 2021 , Other)-