Browsing by Author "Malki, Ahmed"
Now showing items 1-20 of 34
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Antitumor Activities of the Novel Isosteviol Derivative 10C Against Liver Cancer
( International Institute of Anticancer Research , 2017 , Article)Background/Aim. Hepatocellular carcinoma (HCC) is the most common type of liver cancer and the fifth most common primary malignancy with worldwide increasing incidence. The current study aims to investigate the anticancer ... -
Artificial Intelligence Readiness, Perceptions, and Educational Needs Among Dental Students: A Cross-Sectional Study
( Wiley , 2024 , Article)Objectives: With Artificial Intelligence (AI) profoundly affecting education, ensuring that students in health disciplines are ready to embrace AI is essential for their future workforce integration. This study aims to ... -
Association between metabolically healthy obesity and metastasis in lung cancer patients – a systematic review and meta-analysis
( Frontiers Media , 2023 , Article Review)Background: Many clinical trials have looked at the relationship between obesity and lung cancer (LC), however, there is scarcity of literature specifically addressing the association between metabolically healthy obesity ... -
Association between Soft Drink Consumption and Aggressive Behaviour among a Quarter Million Adolescents from 64 Countries Based on the Global School-Based Student Health Survey (GSHS)
( MDPI , 2020 , Article)Soft drink consumption has become a significant public health concern that is associated with various adverse health outcomes.We aim to examine the association between soft drink consumption and aggressive behavior among ... -
Associations between perceived occupational stressors and symptoms severity of depression, anxiety and stress among academic faculty: First cross-sectional study from Qatar
( BioMed Central Ltd , 2024 , Article)Background: Mental health concerns among university faculty are on the rise, with reports of anxiety, depression, and occupational stress, impacting the higher education community. In Qatar, an assessment of faculty mental ... -
Biological and biomedical functions of Penta-O-galloyl-D-glucose and its derivatives
( Springer Nature , 2014 , Article Review)Penta-O-galloyl-D-glucose (PGG) is a simple hydrolysable tannin in plants. PGG exists in two anomeric forms, α-PGG and β-PGG. While β-PGG can be found in a wide variety of plants, α-PGG is rather rare in nature. Numerous ... -
Clinical Utility and Cost Effectiveness of Complement 3 and Complement 4 in Different Clinical Subspecialties in Hamad Medical Corporation
( Qatar University Press , 2020 , Poster)Background: Complement system is one of ancient innate immune system in our body fighting against pathogens and foreign bodies. It is activated by either one of its three pathways, classical, alternative or lectin. Because ... -
Discovery of Novel Pyridine Derivatives as Anti-Cancer Agents
(2015 , Master Thesis)The International Agency for Research on Cancer indicated that cancer burden was raised in 2012 to 14.1 million incidence cases and 8.2 mortality cases. Consequently, novel approaches are urgently required for further ... -
E-Cigarette Liquid Provokes Significant Embryotoxicity and Inhibits Angiogenesis.
( MDPI , 2020 , Article)E-cigarette smoking (ECS) is a new method of tobacco smoking that is gaining popularity as it is thought to be a "healthy method" of tobacco consumption. The adverse outcomes of ECS on the respiratory and cardiovascular ... -
Editorial: Vascular Endothelial Growth Factor Inhibitors: Blocking Angiogenesis and Improving Outcomes.
( OMICS International , 2015 , Article)Tumor tissues are just like normal tissues; require nutrients, oxygen and the ability to evacuate waste products and CO2, the process of angiogenesis or (tumor-associated vascularization) addresses these needs to tumor ... -
The effect of novel nitrogen-based chalcone analogs on colorectal cancer cells: Insight into the molecular pathways
( Elsevier , 2024 , Article)In colorectal cancer (CRC), aberrations in KRAS are associated with aggressive tumorigenesis and an overall low survival rate because of chemoresistance and adverse effects. Ergo, complementary, and integrative medicines ... -
Enhancing Cardiovascular Health and Functional Recovery in Stroke Survivors: A Randomized Controlled Trial of Stroke-Specific and Cardiac Rehabilitation Protocols for Optimized Rehabilitation
( MDPI , 2023 , Article)Background: Stroke is a major contributor to disability and mortality globally. It leads to physical impairments, including weakness and cardiovascular deconditioning, posing significant challenges to stroke survivors’ ... -
High-Risk HPV Oncoproteins and PD-1/PD-L1 Interplay in Human Cervical Cancer: Recent Evidence and Future Directions
( Frontiers Media , 2020 , Article)Cervical cancer is the fourth most common malignancy in women worldwide and a leading cause of cancer-related mortality in developing countries. Important etiological factors in this cancer are high-risk human papillomaviruses ... -
In vitro and in vivo efficacy of a novel quinuclidinone derivative against breast cancer
( International Institute of Anticancer Research , 2014 , Article)Previously, our laboratory reported on novel quinuclidinone derivatives that cause cytotoxicity in human non-small lung carcinoma epithelial cells null for p53 (H1299). The current study aims to investigate the effect of ... -
IN-DEPTH CHARACTERIZATION OF MESENCHYMAL STEM CELLS-DERIVED EXTRACELLULAR VESICLES USING QUANTITATIVE PROTEOMICS
(2016 , Master Thesis)As they home in on injured tissue, modulate the immune system and support tissue repairing, mesenchymal stem cells (MSCs) are considered a promising tool for many therapeutic applications. In vitro, MSCs have been shown ... -
Integrating pharmacogenomics in three Middle Eastern countries' healthcare (Lebanon, Qatar, and Saudi Arabia): Current insights, challenges, and strategic directions
( Public Library of Science , 2025 , Article)Background and objectives Pharmacogenomics (PGx) leverages genomic information to tailor drug therapies, enhancing precision medicine. Despite global advancements, its implementation in Lebanon, Qatar, and Saudi Arabia ... -
Mental health interventions affecting university faculty: a systematic review and meta-analysis
( BioMed Central Ltd , 2024 , Article Review)Background: While there is growing evidence highlighting the prevalence of mental health concerns among university faculty, few studies have examined mental health interventions in this population. The objective of this ... -
Microfluidics integrated biosensors: A leading technology towards lab-on-a-chip and sensing applications
( Multidisciplinary Digital Publishing Institute (MDPI) , 2015 , Article)A biosensor can be defined as a compact analytical device or unit incorporating a biological or biologically derived sensitive recognition element immobilized on a physicochemical transducer to measure one or more analytes. ... -
Molecular Mechanisms of Colon Cancer Progression and Metastasis: Recent Insights and Advancements.
( MDPI , 2020 , Article Review)Colorectal cancer (CRC), the third most common type of cancer, is the second leading cause of cancer-related mortality rates worldwide. Although modern research was able to shed light on the pathogenesis of CRC and provide ... -
New 3-Cyano-2-Substituted Pyridines Induce Apoptosis in MCF 7 Breast Cancer Cells
( Multidisciplinary Digital Publishing Institute (MDPI) , 2016 , Article)The synthesis of new 3-cyano-2-substituted pyridines bearing various pharmacophores and functionalities at position 2 is described. The synthesized compounds were evaluated for their in vitro anti-cancer activities on five ...
