Browsing by Author "Mutlu, Onur"
Now showing items 1-14 of 14
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Characterization of Flow Structure and Wall Shear Stress in Patient-Specific Abdominal Aortic Aneurysm Phantom Using Particle Image Velocimetry
( American Society of Mechanical Engineers (ASME) , 2025 , Article)Abdominal aortic aneurysm (AAA) is an irreversible dilation of the abdominal aorta that carries a significant risk of rupture if not adequately screened and treated. This condition poses a severe threat, with a mortality ... -
Experimental Assessment of Cardiovascular Physiology in the Chick Embryo.
( American Association for Anatomy Journals , 2023 , Article Review)High resolution assessment of cardiac functional parameters is crucial in translational animal research. The chick embryo is a historically well-used in vivo model for cardiovascular research due to its many practical ... -
Fetal ECG extraction from maternal ECG using deeply supervised LinkNet++ model
( Elsevier , 2023 , Article)Fetal heart monitoring and early disease detection using non-invasive fetal electrocardiograms (fECG) can help substantially to reduce infant death through improved diagnosis of Coronary Heart Disease (CHD) in the fetus. ... -
Finite Element Analysis of Evolut Transcatheter Heart Valves: Effects of Aortic Geometries and Valve Sizes on Post-TAVI Wall Stresses and Deformations
( MDPI , 2025 , Article)Background/Objectives: For transcatheter aortic valve implantation (TAVI) therapy, a catheter-guided crimped valve is deployed into the aortic root. Valve types such as Edwards balloon-expandable valves and Medtronic ... -
Finite Element Analysis of Self Expanding Transcatheter Aortic Valves reveals Increased Stent contact Pressure is Associated with Higher Conduction Abnormality Risk
( The Royal Society , 2025 , Conference)For transcatheter aortic valve implantation (TAVI), selecting optimal valve size and implantation depth within aortic root is crucial for preventing complications, such as conduction problems and paravalvular leak. ... -
Fluid Flow Characteristics of Healthy and Calcified Aortic Valves Using Three-Dimensional Lagrangian Coherent Structures Analysis
( MDPI , 2021 , Article)Aortic valve calcification is an important cardiovascular disorder that deteriorates the accurate functioning of the valve leaflets. The increasing stiffness due to the calcification prevents the complete closure of the ... -
Investigation of potential rupture locations for abdominal aortic aneurysms with patient-specific computational fluid dynamic analysis approach
( Qatar University Press , 2021 , Poster)Background: About 18 million people die each year from cardiovascular disorders, accounting for 31% of all deaths worldwide. Abdominal Aortic Aneurysm (AAA) is a serious clinical condition manifested as dilation of the ... -
Investigation of the effect of anticoagulant usage in the flow diverter stent treatment of the patient-specific cerebral aneurysm using the Lagrangian coherent structures
( Elsevier , 2021 , Article)Anticoagulants are prescribed to the flow diverter treated patients to diminish the risk of embolism in the arteries. In the present study, digital subtraction angiography images of a 49-year-old female patient with a left ... -
Latest Developments in Adapting Deep Learning for Assessing TAVR Procedures and Outcomes
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)Aortic valve defects are among the most prevalent clinical conditions. A severely damaged or non-functioning aortic valve is commonly replaced with a bioprosthetic heart valve (BHV) via the transcatheter aortic valve ... -
Material modeling and recent findings in transcatheter aortic valve implantation simulations
( Elsevier , 2024 , Article Review)Background and objective: Transcatheter aortic valve implantation (TAVI) has significantly transformed the management of aortic valve (AV) diseases, presenting a minimally invasive option compared to traditional surgical ... -
An optimized CT-dense agent perfusion and micro-CT imaging protocol for chick embryo developmental stages.
( BMC , 2024 , Article)Compared to classical techniques of morphological analysis, micro-CT (μ-CT) has become an effective approach allowing rapid screening of morphological changes. In the present work, we aimed to provide an optimized micro-CT ... -
Oscillatory Disturbed Flow Enhances Inflammatory and Oxidative Stress Markers in Endothelial Cells
( MDPI , 2025 , Article)Hemodynamics significantly impact the biology of endothelial cells (ECs) lining the blood vessels. ECs are exposed to various hemodynamic forces, particularly frictional shear stress from flowing blood. While physiological ... -
Patient Specific Transcatheter Aortic Valve Replacement Therapy Pathway with Computational Fluid Structure Interaction Analysis
( Qatar University Press , 2021 , Poster)Total cardiovascular disease (CVD) prevalence has risen dramatically from 271 million in 1990 to 523 million in 2019, and CVD fatalities rose gradually from 12.1 million in 1990 to 18.6 million in 2019. According to American ... -
Rapid wall shear stress prediction for aortic aneurysms using deep learning: a fast alternative to CFD
( Springer Nature , 2025 , Article)Abstract: Aortic aneurysms pose a significant risk of rupture. Previous research has shown that areas exposed to low wall shear stress (WSS) are more prone to rupture. Therefore, precise WSS determination on the aneurysm ...
