Browsing by Author "Al-Ruweidi, Mahmoud Khatib A.A."
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Application of a flow-induced stress wave and investigation of associated injuries on cell monolayers using a parallel plate flow chamber
Shurbaji, Samar; Al-Ruweidi, Mahmoud Khatib A.A.; Ali, Fatma Hassan; Benslimane, Fatiha M.; Yalcin, Huseyin C. ( MDPI , 2020 , Article)© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Parallel plate flow chambers are widely used to expose cultured cells to physiological flows for the investigation of a variety of diseases. These applications ... -
Autoimmune Diseases of the GI Tract Part I: Etiology and Pathophysiology
Al-Ruweidi, Mahmoud Khatib A.A.; Khater, Nada; Alkaabi, Haya Rashid; Hasan, Maram; Yalcin, Huseyin C. ( IntechOpen , 2022 , Book chapter)Autoimmune diseases have emerged as a pandemic in our modern societies, especially after World War II. There are currently more than 80 autoimmune diseases that compromise the lives of millions of patients around the world. ... -
Autoimmune Diseases of the GI Tract Part II: Emergence of Diagnostic Tools and Treatments
Al-Ruweidi, Mahmoud Khatib A.A.; Khater, Nada; Alkaabi, Haya Rashid; Hasan, Maram; Murtaza, Mohammed; Yalcin, Huseyin C.... more authors ... less authors ( IntechOpen , 2022 , Book chapter)Autoimmune diseases (AD) have emerged as a pandemic in our modern societies, especially after the World War II. In part I, we have reviewed five main diseases and shed light on different aspects from introducing the concept ... -
Dexamethasone and transdehydroandrosterone significantly reduce pulmonary epithelial cell injuries associated with mechanical ventilation.
Al-Ruweidi, Mahmoud Khatib A A; Ali, Fatma Hassan; Shurbaji, Samar; Popelka, Anton; Yalcin, Huseyin C ( American Physiological Society , 2021 , Article)Many patients who suffer from pulmonary diseases cannot inflate their lungs normally, as they need mechanical ventilation (MV) to assist them. The stress associated with MV can damage the delicate epithelium in small airways ... -
Do changes in ace-2 expression affect sars-cov-2 virulence and related complications: A closer look into membrane-bound and soluble forms
Yalcin, Huseyin C.; Sukumaran, Vijayakumar; Al-Ruweidi, Mahmoud Khatib A.A.; Shurbaji, Samar ( MDPI , 2021 , Article Review)The SARS-CoV-2 virus utilizes angiotensin converting enzyme (ACE-2) for cell entry and infection. This enzyme has important functions in the renin-angiotensin aldosterone system to preserve cardiovascular function. In ... -
Microfluidic-based virus detection methods for respiratory diseases
Tarim, E. Alperay; Karakuzu, Betul; Oksuz, Cemre; Sarigil, Oyku; Kizilkaya, Melike; Al-Ruweidi, Mahmoud Khatib A.A.; Yalcin, Huseyin Cagatay; Ozcivici, Engin; Tekin, H. Cumhur... more authors ... less authors ( Springer , 2021 , Article)With the recent SARS-CoV-2 outbreak, the importance of rapid and direct detection of respiratory disease viruses has been well recognized. The detection of these viruses with novel technologies is vital in timely prevention ... -
Soluble ACE2 and angiotensin II levels are modulated in hypertensive COVID-19 patients treated with different antihypertension drugs.
A Elrayess, Mohamed; T Zedan, Hadeel; A Alattar, Rand; Abusriwil, Hatem; Al-Ruweidi, Mahmoud Khatib A A; Almuraikhy, Shamma; Parengal, Jabeed; Alhariri, Bassem; Yassine, Hadi M; A Hssain, Ali; Nair, Arun; Al Samawi, Musaed; Abdelmajid, Alaaeldin; Al Suwaidi, Jassim; Omar Saad, Mohamed; Al-Maslamani, Muna; Omrani, Ali S; Yalcin, Huseyin C... more authors ... less authors ( Taylor and Francis , 2022 , Article)This study examines the effect of antihypertensive drugs on ACE2 and Angiotensin II levels in hypertensive COVID-19 patients. Hypertension is a common comorbidity among severe COVID-19 patients. ACE2 expression can be ... -
Soluble ACE2 and Angiotensin II levels Modulated in Hypertensive COVID-19 Patients treated with different Antihypertension Drugs
Yalcin, Huseyin C.; Elrayess, Mohamed A; Al-Jighefee, Hadeel T; Al-Ruweidi, Mahmoud Khatib A. A.; Almuraikhy, Shamma; Yassine, Hadi M.... more authors ... less authors ( Qatar University Press , 2021 , Poster)Hypertension is a major risk factor and common comorbidity among severe Coronavirus Disease 2019 (COVID-19) patients. Prominent antihypertensive drugs, such as angiotensin-converting-enzyme inhibitors (ACEi) and angiotensin ...