Browsing by Author "Nasrallah, Leila"
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The effect of clopidogrel and aspirin on the severity of traumatic brain injury in a rat model
Firas, Kobeissy; Mallah, Khalil; Zibara, Kazem; Dakroub, Fatima; Dalloul, Zeinab; Nasser, Mohammad; Nasrallah, Leila; Mallah, Zahraa; El-Achkar, Ghewa A.; Ramadan, Naify; Mohamed, Wael; Mondello, Stefania; Darwish, Hala; Hamade, Eva; Habib, Aida... more authors ... less authors ( Elsevier , 2022 , Article)Traumatic Brain Injury (TBI) is one of the leading causes of death and disability worldwide. Aspirin (ASA) and clopidogrel (CLOP) are antiplatelet agents that inhibit platelet aggregation. They are implicated in worsening ... -
Mitoquinone supplementation alleviates oxidative stress and pathologic outcomes following repetitive mild traumatic brain injury at a chronic time point
Maha, Tabet; El-Kurdi, Marya; Haidar, Muhammad Ali; Nasrallah, Leila; Reslan, Mohammad Amine; Shear, Deborah; Pandya, Jignesh D.; El-Yazbi, Ahmed F.; Sabra, Mirna; Mondello, Stefania; Mechref, Yehia; Shaito, Abdullah; Wang, Kevin K.; El-Khoury, Riyad; Kobeissy, Firas... more authors ... less authors ( Elsevier , 2022 , Article)Traumatic brain injury (TBI) is a major cause of disability and death. Mild TBI (mTBI) constitutes ~75% of all TBI cases. Repeated exposure to mTBI (rmTBI), leads to the exacerbation of the symptoms compared to single mTBI. ... -
Modulation of Neuro-Inflammatory Signals in Microglia by Plasma Prekallikrein and Neuronal Cell Debris
Jaffa, Aneese A.; Jaffa, Miran A.; Moussa, Mayssam; Ahmed, Ibrahim A.; Karam, Mia; Aldeen, Kawthar Sharaf; Al Sayegh, Rola; El-Achkar, Ghewa A.; Nasrallah, Leila; Yehya, Yara; Habib, Aida; Ziyadeh, Fuad N.; Eid, Ali H.; Kobeissy, Firas H.... more authors ... less authors ( Frontiers Media , 2021 , Article)Microglia, the resident phagocytes of the central nervous system and one of the key modulators of the innate immune system, have been shown to play a major role in brain insults. Upon activation in response to neuroinflammation, ... -
Traumatic Brain Injury Can Affect Emotions and Behaviors
Shakkour, Zaynab; Habashy, Karl John; Haidar, Muhammad Ali; Nasrallah, Leila; Tabet, Maha; Yehya, Yara; Sarieddine, Rana; El Hayek, Samer; Shaito, Abdullah; Kobeissy, Firas... more authors ... less authors ( Frontiers Media , 2023 , Article)Proper brain functioning is responsible for our feelings, behavior, and thinking. However, an injury to the brain can disrupt brain function, which can affect our emotions and behaviors. A traumatic brain injury (TBI) can ...