Browsing by Author "Elrayess, Mohamed A."
Now showing items 1-20 of 93
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Advancements in precision medicine: multi-omics approach for tailored metformin treatment in type 2 diabetes
Anwardeen, Najeha Rizwana; Naja, Khaled; Elrayess, Mohamed A. ( Frontiers Media SA , 2024 , Article Review)Metformin has become the frontline treatment in addressing the significant global health challenge of type 2 diabetes due to its proven effectiveness in lowering blood glucose levels. However, the reality is that many ... -
Age and sport intensity-dependent changes in cytokines and telomere length in elite athletes
Sellami, Maha; Al-Muraikhy, Shamma; Al-Jaber, Hend; Al-Amri, Hadaia; Al-Mansoori, Layla; Mazloum, Nayef A.; Donati, Francesco; Botre, Francesco; Elrayess, Mohamed A.... more authors ... less authors ( MDPI , 2021 , Article Review)Background: Exercise-associated immune response plays a crucial role in the aging process. The aim of this study is to investigate the effect of sport intensity on cytokine levels, oxidative stress markers and telomere ... -
Amniotic stem cells as a source of regenerative medicine to treat female infertility
Naeem, Aisha; Gupta, Nikita; Naeem, Usra; Elrayess, Mohamed A.; Albanese, Chris ( Springer , 2022 , Article Review)Impaired reproductive health is a worldwide problem that affects the psychological well-being of a society. Despite the technological developments to treat infertility, the global infertility rate is increasing significantly. ... -
Antioxidative Stress Metabolic Pathways in Moderately Active Individuals
Almuraikhy, Shamma; Anwardeen, Najeha; Doudin, Asmma; Sellami, Maha; Domling, Alexander; Agouni, Abdelali; Althani, Asmaa A.; Elrayess, Mohamed A.... more authors ... less authors ( MDPI , 2023 , Article)Physical activity (PA) is known to have beneficial effects on health, primarily through its antioxidative stress properties. However, the specific metabolic pathways that underlie these effects are not fully understood. ... -
apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes.
Ramanjaneya, Manjunath; Butler, Alexandra E; Bashir, Mohammed; Bettahi, Ilham; Moin, Abu Saleh Md; Ahmed, Lina; Elrayess, Mohamed A; Hunt, Steven C; Atkin, Stephen L; Abou-Samra, Abdul Badi... more authors ... less authors ( BMJ Publishing Group , 2021 , Article)Pregnant women with gestational diabetes mellitus (GDM) are at risk of adverse outcomes, including gestational hypertension, pre-eclampsia, and preterm delivery. This study was undertaken to determine if apolipoprotein ... -
Arrhythmia-Associated Calmodulin E105A Mutation Alters the Binding Affinity of CaM to a Ryanodine Receptor 2 CaM-Binding Pocket
Thanassoulas, Angelos; Theodoridou, Maria; Barrak, Laila; Riguene, Emna; Alyaarabi, Tamader; Elrayess, Mohamed A.; Lai, F. Anthony; Nomikos, Michail... more authors ... less authors ( MDPI , 2023 , Article)Calmodulin (CaM) is a small, multifunctional calcium (Ca2+)-binding sensor that binds and regulates the open probability of cardiac ryanodine receptor 2 (RyR2) at both low and high cytosolic Ca2+ concentrations. Recent ... -
Assessment of Serum Cytokines and Oxidative Stress Markers in Elite Athletes Reveals Unique Profiles Associated With Different Sport Disciplines
Sohail, Muhammad U.; Al-Mansoori, Layla; Al-Jaber, Hend; Georgakopoulos, Costas; Donati, Francesco; Botrè, Francesco; Sellami, Maha; Elrayess, Mohamed A.... more authors ... less authors ( Frontiers Media , 2020 , Article)© Copyright © 2020 Sohail, Al-Mansoori, Al-Jaber, Georgakopoulos, Donati, Botrè, Sellami and Elrayess. Objectives: Circulating cytokines and oxidative stress markers vary in response to different exercise regimens. This ... -
Association between antioxidant metabolites and N-terminal fragment brain natriuretic peptides in insulin-resistant individuals.
Anwardeen, Najeha; Naja, Khaled; Elrayess, Mohamed A ( Lippincott, Williams & Wilkins , 2024 , Article)Oxidative stress plays a pivotal role in the development of metabolic syndrome, including heart failure and insulin resistance. The N-terminal fragment of brain natriuretic peptide (NT-proBNP) has been associated with ... -
Association of Complement-Related Proteins in Subjects With and Without Second Trimester Gestational Diabetes.
Ramanjaneya, Manjunath; Butler, Alexandra E; Alkasem, Meis; Bashir, Mohammed; Jerobin, Jayakumar; Godwin, Angela; Moin, Abu Saleh Md; Ahmed, Lina; Elrayess, Mohamed A; Hunt, Steven C; Atkin, Stephen L; Abou-Samra, Abdul-Badi... more authors ... less authors ( Frontiers Media , 2021 , Article)Gestational Diabetes Mellitus (GDM) development is related to underlying metabolic syndrome that is associated with elevated complement C3 and C4. Elevated C3 levels have been associated with preeclampsia and the development ... -
The association of HFE gene H63D polymorphism with endurance athlete status and aerobic capacity: novel findings and a meta-analysis.
Semenova, Ekaterina A; Miyamoto-Mikami, Eri; Akimov, Egor B; Al-Khelaifi, Fatima; Murakami, Haruka; Zempo, Hirofumi; Kostryukova, Elena S; Kulemin, Nikolay A; Larin, Andrey K; Borisov, Oleg V; Miyachi, Motohiko; Popov, Daniil V; Boulygina, Eugenia A; Takaragawa, Mizuki; Kumagai, Hiroshi; Naito, Hisashi; Pushkarev, Vladimir P; Dyatlov, Dmitry A; Lekontsev, Eugene V; Pushkareva, Yuliya E; Andryushchenko, Liliya B; Elrayess, Mohamed A; Generozov, Edward V; Fuku, Noriyuki; Ahmetov, Ildus I... more authors ... less authors ( Springer , 2020 , Article)Iron is an important component of the oxygen-binding proteins and may be critical to optimal athletic performance. Previous studies have suggested that the G allele of C/G rare variant (rs1799945), which causes H63D amino ... -
Author Correction: Metabolic GWAS of elite athletes reveals novel genetically-influenced metabolites associated with athletic performance (Scientific Reports, (2019), 9, 1, (19889), 10.1038/s41598-019-56496-7)
Al-Khelaifi, Fatima; Diboun, Ilhame; Donati, Francesco; Botrè, Francesco; Abraham, David; Hingorani, Aroon; Albagha, Omar; Georgakopoulos, Costas; Suhre, Karsten; Yousri, Noha A.; Elrayess, Mohamed A.... more authors ... less authors ( Nature Research , 2020 , Article)The Acknowledgements section in this Article is incomplete. "This study was funded by Qatar National Research Fund (QNRF), Grant number NPRP7-272-1-041 (MAE, KS, CG and FB). The funders had no role in study design, data ... -
Comparing levels of metabolic predictors of coronary heart disease between healthy lean and overweight females
Abu-El-ruz, Rasha; Abdel-Rahman, Manar E.; Atkin, Stephen L.; Elrayess, Mohamed A. ( MDPI AG , 2021 , Article)Screening for the metabolomic signature of coronary heart disease (CHD) before disease onset could help in early diagnosis and potentially disease prevention. In this study, the levels of 17 CHD metabolic biomarkers in ... -
Comparing Levels of Metabolic Predictors of Coronary Heart Disease between Healthy Lean and Overweight Females.
Abu-El-Ruz, Rasha; Abdel-Rahman, Manar E; Atkin, Stephen L; Elrayess, Mohamed A ( MDPI , 2021 , Article)Screening for the metabolomic signature of coronary heart disease (CHD) before disease onset could help in early diagnosis and potentially disease prevention. In this study, the levels of 17 CHD metabolic biomarkers in ... -
Comparing metabolic profiles between female endurance athletes and non-athletes reveals differences in androgen and corticosteroid levels
Amneh H., Tarkhan; Anwardeen, Najeha R.; Sellami, Maha; Donati, Francesco; Botrè, Francesco; de la Torre, Xavier; Elrayess, Mohamed A.... more authors ... less authors ( Elsevier , 2022 , Article)Endurance training is associated with physiological changes in elite athletes, but little is known about female-specific effects of endurance training. Despite the significant rise in female sports participation, findings ... -
Comparing Methods for Induction of Insulin Resistance in Mouse 3T3-L1 Cells
Al-Jaber, Hend; Al-Muraikhy, Shamma; Jabr, Aldana; Yousef, Aisha; Anwardeen, Najeha R.; Elrayess, Mohamed A.; Al-Mansoori, Layla... more authors ... less authors ( Bentham Science Publishers , 2025 , Article)Cell culture plays a crucial role in addressing fundamental research questions, particularly in studying insulin resistance (IR) mechanisms. Multiple in vitro models are utilized for this purpose, but their technical ... -
Comparing the Metabolic Profiles Associated with Fitness Status between Insulin-Sensitive and Insulin-Resistant Non-Obese Individuals
AlMuraikhy, Shamma; Anwardeen, Najeha; Naeem, Aisha; Sellami, Maha; Domling, Alexander; Agouni, Abdelali; Elrayess, Mohamed A... more authors ... less authors ( MDPI , 2022 , Article)(1) Background: Young non-obese insulin-resistant (IR) individuals could be at risk of developing metabolic diseases including type 2 diabetes mellitus. The protective effect of physical activity in this apparently healthy ... -
Comparing the metabolic signatures of obesity defined by waist circumference, waist-hip ratio, or BMI
Al Hariri, Moustafa; Al-Sulaiti, Haya; Anwardeen, Najeha; Naja, Khaled; Elrayess, Mohamed A. ( John Wiley and Sons Inc , 2024 , Article)Objective: Measuring obesity is crucial for assessing health risks and developing effective prevention and treatment strategies. The most common methods used to measure obesity include BMI, waist circumference, and waist-hip ... -
A comparison of isolation and culture protocols for human amniotic mesenchymal stem cells.
Naeem, Aisha; Gupta, Nikita; Naeem, Usra; Khan, Muhammad Jawad; Elrayess, Mohamed A; Cui, Wanxing; Albanese, Chris... more authors ... less authors ( Taylor and Francis , 2022 , Article Review)The successful translation of mesenchymal stem cells (MSCs) from bench to bedside is predicated upon their regenerative capabilities and immunomodulatory potential. Many challenges still exist in making MSCs a viable and ... -
Correction to: Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels (Emergent Materials, (2025), 8, 2, (985-998), 10.1007/s42247-024-00888-7)
Al-Sulaiti, Haya; Ismail, Roua; Anwardeen, Najeha; Al-Saei, Aisha Nasser J.M.; Alkilany, Alaaldin; Elrayess, Mohamed A.; Rachid, Ousama... more authors ... less authors ( Springer Nature , 2025 , Article)The original version of this publication contained wrong texts in the Acknowledgement section and in the Author contributions section. In addition, the article note on page 1 has been corrected. These errors have been ... -
Corrigendum: Association of Complement-Related Proteins in Subjects With and Without Second Trimester Gestational Diabetes (Front. Endocrinol., (2021), 12, (641361), 10.3389/fendo.2021.641361)
Ramanjaneya, Manjunath; Butler, Alexandra E.; Alkasem, Meis; Bashir, Mohammed; Jerobin, Jayakumar; Godwin, Angela; Moin, Abu Saleh Md; Ahmed, Lina; Elrayess, Mohamed A.; Hunt, Steven C.; Atkin, Stephen L.; Abou-Samra, Abdul Badi... more authors ... less authors ( Frontiers Media S.A. , 2021 , Article)In the original article, there was an error. One of the funders wasmissed out in the Acknowledgements. A correction has been made to the Acknowledgements section. “The authors would like to thank Qatar Metabolic Institute, ...



















