تصفح حسب المؤلف "Al Moustafa, Ala-Eddin"
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A comprehensive review on the antiviral activities of chalcones
Elkhalifa, Dana; Al-Hashimi, Israa; Al Moustafa, Ala-Eddin; Khalil, Ashraf ( Taylor and Francis Ltd. , 2021 , Article)Some viral outbreaks have plagued the world since antiquity, including the most recent COVID-19 pandemic. The continuous spread and emergence of new viral diseases have urged the discovery of novel treatment options that ... -
A comprehensive review summarizing the recent biomedical applications of functionalized carbon nanofibers
Abdo, Ghada G.; Zagho, Moustafa M.; Al Moustafa, Ala-Eddin; Khalil, Ashraf; Elzatahry, Ahmed A. ( John Wiley and Sons Inc , 2021 , Article)Since the discovery and fabrication of carbon nanofibers (CNFs) over a decade ago, scientists foster to discover novel myriad potential applications for this material in both biomedicine and industry. The unique economic ... -
Association between waterpipe smoking and obesity: Population-based study in Qatar
Alkeilani, Abdulla A.; Khalil, Abdelrahman A.; Azzan, Afaf M.; Al-Khal, Noof A.; Al-Nabit, Noora H.; Talab, Omar M.; Al-Hajri, Rahaf A.; Rahmoon, Samreen M.; Ashour, Anas A.; Gupta, Ishita; Al Moustafa, Ala-Eddin... more authors ... less authors ( European Publishing , 2022 , Article)Introduction: Over the past decade obesity prevalence has been increasing rapidly in the Gulf region (GR) including Qatar, becoming one of the major health issues in the region. Concomitantly, waterpipe (WP) smoking is ... -
Breast Cancer During Pregnancy: A Marked Propensity to Triple-Negative Phenotype.
Allouch, Soumaya; Gupta, Ishita; Malik, Shaza; Al Farsi, Halema F; Vranic, Semir; Al Moustafa, Ala-Eddin... more authors ... less authors ( Frontiers Media , 2020 , Article)Breast and cervical cancers comprise 50% of all cancers during pregnancy. In particular, gestational breast cancer is considered one of the most aggressive types of cancers, which is a rare but fatal disease. However, the ... -
Co-Incidence of Epstein-Barr Virus and High-Risk Human Papillomaviruses in Cervical Cancer of Syrian Women.
Al-Thawadi, Hamda; Ghabreau, Lina; Aboulkassim, Tahar; Yasmeen, Amber; Vranic, Semir; Batist, Gerald; Al Moustafa, Ala-Eddin... more authors ... less authors ( Frontiers Media , 2018 , Article)Epstein-Barr virus (EBV) has been recently shown to be co-present with high-risk human papillomaviruses (HPVs) in human cervical cancer; thus, these oncoviruses play an important role in the initiation and/or progression ... -
Co-Incidence of Human Papillomaviruses and Epstein-Barr Virus is Associated with Advanced Tumor Stage: A Tissue Microarray Study of Head and Neck Cancers
Gupta, Ishita; Al-Thawadi, Hamda A.; Skenderi, Faruk; Malki, Mohammed I.; Vranic, Semir; Al-Moustafa, Ala-Eddin... more authors ... less authors ( Qatar University Press , 2020 , Poster)Background: Human papillomaviruses (HPVs) and Epstein-Barr virus (EBV), are known oncoviruses and can be co-present and hence cooperate in the development of human carcinomas, including head and neck. Methods: We herein ... -
Co-incidence of Human Papillomaviruses and Epstein-Barr Virus Is Associated With High to Intermediate Tumor Grade in Human Head and Neck Cancer in Syria.
Gupta, Ishita; Ghabreau, Lina; Al-Thawadi, Hamda; Yasmeen, Amber; Vranic, Semir; Al Moustafa, Ala-Eddin; Malki, Mohammed I... more authors ... less authors ( Frontiers Media , 2020 , Article)High-risk human papillomaviruses (high-risk HPVs) have been recently reported to be co-present with Epstein-Barr virus (EBV) in different types of human cancers including head and neck (HN), where they can cooperate in the ... -
Co-presence of Epstein-Barr virus and high-risk human papillomaviruses in Syrian colorectal cancer samples.
Malki, Mohammed I; Gupta, Ishita; Fernandes, Queenie; Aboulkassim, Tahar; Yasmeen, Amber; Vranic, Semir; Al Moustafa, Ala-Eddin; Al-Thawadi, Hamda A... more authors ... less authors ( Taylor & Francis , 2020 , Article)We recently performed two studies exploring the presence of Epstein-Barr virus (EBV) and high-risk human papillomaviruses (HPVs) types 16, 18, 31, 33 and 35 in human colorectal cancers from the Syrian population. Herein, ... -
The co-presence of high-risk human papillomaviruses and Epstein-Barr virus is linked with tumor grade and stage in Qatari women with breast cancer.
Gupta, Ishita; Jabeen, Ayesha; Al-Sarraf, Reem; Farghaly, Hanan; Vranic, Semir; Sultan, Ali A; Al Moustafa, Ala-Eddin; Al-Thawadi, Hamda... more authors ... less authors ( Taylor and Francis , 2020 , Article)High-risk human papillomaviruses (HPV) can be present and cooperate with Epstein-Barr virus (EBV) to promote the onset and/or progression of various cancers including cervical, breast, head and neck as well as colorectal. ... -
Co-presence of human papillomaviruses and Epstein-Barr virus is linked with advanced tumor stage: a tissue microarray study in head and neck cancer patients.
Al-Thawadi, Hamda; Gupta, Ishita; Jabeen, Ayesha; Skenderi, Faruk; Aboulkassim, Tahar; Yasmeen, Amber; Malki, Mohammed I; Batist, Gerald; Vranic, Semir; Al Moustafa, Ala-Eddin... more authors ... less authors ( BMC , 2020 , Article)Human papillomaviruses (HPVs) and Epstein-Barr virus (EBV), known oncoviruses, can be co-present and cooperate in the initiation and/or progression of human carcinomas, including head and neck. Based on this fact, we ... -
Co-prevalence of Epstein-Barr virus and high-risk human papillomaviruses in Syrian women with breast cancer.
Al Moustafa, Ala-Eddin; Al-Antary, Noor; Aboulkassim, Tahar; Akil, Nizar; Batist, Gerald; Yasmeen, Amber... more authors ... less authors ( Taylor & Francis , 2016 , Article)ABSTRAT We recently performed 2 studies viewing the presence of Epstein-Barr virus (EBV) and high-risk human papillomaviruses (HPVs) types 16, 18, 31, 33 and 35 in human breast cancer in the Syrian population. Herein, we ... -
CO-PREVALENCE OF HUMAN PAPILLOMAVIRUS AND EPSTEIN BARR VIRUS IN HEALTHY BLOOD DONORS IN QATAR
Gupta, Ishita; Jabeen, Ayesha; Smatti, Maria K.; Al-Thawadi, Hamda A.; Nasrallah, Gheyath K.; Sultan, Ali A.; Al-Khalaf, Moussa; Vranic, Semir; Al-Moustafa, Ala-Eddin... more authors ... less authors ( Qatar University Press , 2020 , Poster)Introduction: Infections with human oncoviruses such as high-risk human papillomaviruses (HPVs) and Epstein-Barr virus (EBV) are globally prevalent in the adult population. Both viruses are strongly associated with several ... -
Coinfection of HPVs Is Associated with Advanced Stage in Colorectal Cancer Patients from Qatar
Fernandes, Queenie; Gupta, Ishita; Murshed, Khaled; Abo Samra, Hayan; Al-Thawadi, Hamda; Vranic, Semir; Petkar, Mahir; Babu, Giridhara Rathnaiah; Al Moustafa, Ala Eddin... more authors ... less authors ( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)High-risk human papillomaviruses (HPVs) are considered risk factors in the origin of several human malignancies, such as breast, cervical, head and neck, as well as colorectal cancers. However, there are no data reported ... -
Comparison of co-presence of Epstein-Barr virus and high-risk human papillomaviruses in colorectal cancers in the Middle East Region
Nagi, Karim; Gupta, Ishita; Al-Thawadi, Hamda A; Jabeen, Ayesha; Malki, Mohammed I.; Vranic, Semir; Al-Moustafa, Ala-Eddin... more authors ... less authors ( Qatar University Press , 2020 , Poster)Background: Several studies have shown the presence of onco viral DNA in colorectal tumor tissues. Viral infection by onco-viruses such as Human papillomaviruses (HPVs) and Epstein-Barr virus (EBV) are well-known to be ... -
Copresence of High-Risk Human Papillomaviruses and Epstein-Barr Virus in Colorectal Cancer: A Tissue Microarray and Molecular Study from Lebanon
Nagi, Karim; Gupta, Ishita; Jurdi, Nawaf; Yasmeen, Amber; Vranić, Semir; Batist, Gerald; Al Moustafa, Ala-Eddin... more authors ... less authors ( MDPI , 2021 , Article)Colorectal cancer (CRC) is the third most common cause of cancer-related deaths worldwide. Human papillomaviruses (HPVs) and Epstein–Barr virus (EBV) have been reported to be present in different types of human cancers ... -
Co‑prevalence of human Papillomaviruses (HPV) and Epstein–Barr virus (EBV) in healthy blood donors from diverse nationalities in Qatar
Gupta, Ishita; Nasrallah, Gheyath; Sharma, Anju; Jabeen, Ayesha; Smatti, Maria; Al‑Thawadi, Hamda; Sultan, Ali; Alkhalaf, Moussa; Vranic, Semir; Al Moustafa, Ala‑Eddin... more authors ... less authors ( BMC , 2020 , Article)Background: Infections by both human oncoviruses, human Papillomaviruses (HPV) and Epstein–Barr virus (EBV) are very common in the adult human population and are associated with various malignancies. While HPV is ... -
Crosstalk between HER2 and PD-1/PD-L1 in Breast Cancer: From Clinical Applications to Mathematical Models.
Padmanabhan, Regina; Kheraldine, Hadeel Shafeeq; Meskin, Nader; Vranic, Semir; Al Moustafa, Ala-Eddin ( Springer , 2020 , Article)Breast cancer is one of the major causes of mortality in women worldwide. The most aggressive breast cancer subtypes are human epidermal growth factor receptor-positive (HER2) and triple-negative breast cancers. Therapies ... -
Dasatinib and PD-L1 inhibitors provoke toxicity and inhibit angiogenesis in the embryo
Maha, Al-Asmakh; Bawadi, Hiba; Hamdan, Munia; Gupta, Ishita; Kheraldine, Hadeel; Jabeen, Ayesha; Rizeq, Balsam; Al Moustafa, Ala-Eddin... more authors ... less authors ( Elsevier , 2021 , Article)Dasatinib is a targeted cancer therapy, while programmed death ligand 1 (PD-L1) inhibitors are a form of immune checkpoint therapy used to treat various types of cancers. Several studies showed the potential efficacy of ... -
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL CHALCONE ANALOGS AS POTENTIAL THERAPEUTIC AGENTS FOR CASTRATION RESISTANT PROSTATE CANCER
HUSSEIN, OLA (2021 , Master Thesis)Prostate cancer (PCa) is the second most frequently diagnosed malignancy, as well as a leading cause of cancer-related mortality in men globally. Despite the initial response to hormonal targeted therapy, the majority of ... -
Design, Synthesis and Biological Evaluation of Novel Chalcone Analogs as Potential Therapeutic Agents for Castration-Resistant Prostate Cancer
Hussein, Ola; Alali, Feras; Al Moustafa, Ala-Eddin; Khalil, Ashraf ( Qatar University Press , 2020 , Poster)Prostate cancer (PCa) is the second most frequently diagnosed malignancy, as well as a leading cause of cancer-related mortality in men globally. Despite the initial response to hormone targeted therapy, the majority of ...