Browsing by Author "Bertok, Tomas"
Now showing items 1-16 of 16
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Analysis of serum glycome by lectin microarrays for prostate cancer patients - a search for aberrant glycoforms
( Springer , 2020 , Article)This is the first work focused on glycoprofiling of whole N- and O- glycome using lectins in an array format applied for analysis of serum samples from healthy individuals, benign prostate hyperplasia (BPH) patients, and ... -
Carboxybetaine Ester Feature as a Platform for Switchable Surface Properties
( Hamad bin Khalifa University Press (HBKU Press) , 2016 , Conference)A lot of strategies for smart approaches on surfaces were applied such as hydrogel layer, polymer brushes or self-assembly monolayers (SAM). [1] Nowadays switchable zwitterionic materials consisting of molecules with ... -
Carboxybetaine Modified Interface for Electrochemical Glycoprofiling of Antibodies Isolated from Human Serum
( American Chemical Society , 2015 , Article)Impedimetric lectin biosensors capable of recognizing two different carbohydrates (galactose and sialic acid) in glycans attached to antibodies isolated from human serum were prepared. The first step entailed the modification ... -
Electrochemical Investigation of Interfacial Properties of Ti3C2Tx MXene Modified by Aryldiazonium Betaine Derivatives
( Frontiers Media S.A. , 2020 , Article)For efficient and effective utilization of MXene such as biosensing or advanced applications, interfacial modification of MXene needs to be considered. To this end, we describe modification of Ti3C2Tx MXene by aryldiazonium-based ... -
Electrochemical performance of Ti3C2Tx MXene in aqueous media: towards ultrasensitive H2O2 sensing
( Elsevier Ltd , 2017 , Article)An extensive characterization of pristine and oxidized Ti3C2Tx (T: O, OH, F) MXene showed that exposure of MXene to an anodic potential in the aqueous solution oxidizes the nanomaterial forming TiO2 layer or TiO2 domains ... -
Glycomics of prostate cancer: updates
( Taylor and Francis Ltd , 2019 , Article)Introduction: Prostate cancer (PCa) is a life-threatening disease affecting millions of men. The current best PCa biomarker (level of prostate-specific antigen in serum) lacks specificity for PCa diagnostics and this is ... -
Glycoprofiling as a novel tool in serological assays of systemic sclerosis: A comparative study with three bioanalytical methods
( Elsevier , 2014 , Article)Systemic sclerosis (SSc) is an autoimmune disease seriously affecting patient’s quality of life. The heterogeneity of the disease also means that identification and subsequent validation of biomarkers of the disease is ... -
Highly stable Ti3C2Tx (MXene)/Pt nanoparticles-modified glassy carbon electrode for H2O2 and small molecules sensing applications
( Elsevier B.V. , 2018 , Article)© 2018 Elsevier B.V. Electrochemical performance of a 2D Ti3C2Tx (MXene, where T: [dbnd]O, –OH, –F) sheets modified with Pt nanoparticles (PtNPs) was investigated. The results showed that Ti3C2Tx/PtNP nanocomposite deposited ... -
Mixed Zwitterion-Based Self-Assembled Monolayer Interface for Impedimetric Glycomic Analyses of Human IgG Samples in an Array Format
( American Chemical Society , 2016 , Article)An impedimetric lectin biosensor for the detection of changes in the glycan structure of antibodies isolated from human serum is here correlated with the progression of rheumatoid arthritis (RA). The biosensor was built ... -
Nanomaterial-based biosensors for detection of prostate specific antigen
( Springer-Verlag Wien , 2017 , Article Review)Screening serum for the presence of prostate specific antigen (PSA) belongs to the most common approach for the detection of prostate cancer. This review (with 156 refs.) addresses recent developments in PSA detection based ... -
Nanotechnology in Glycomics: Applications in Diagnostics, Therapy, Imaging, and Separation Processes
( John Wiley and Sons Inc. , 2017 , Article Review)This review comprehensively covers the most recent achievements (from 2013) in the successful integration of nanomaterials in the field of glycomics. The first part of the paper addresses the beneficial properties of ... -
Novel analysis of glycan structures: Nanoscale approach
( Avestia Publishing , 2016 , Conference)Glycans are complex saccharide moieties covering all cell surfaces - presented on different biomolecules. Almost 75% of all proteins are glycosylated, and these glycans can form thousands of different structures.[1] Moreover, ... -
PH-Switchable Interaction of a Carboxybetaine Ester-Based SAM with DNA and Gold Nanoparticles
( American Chemical Society , 2017 , Article)We describe a self-assembled monolayer (SAM) on a gold surface with a carboxybetaine ester functionality to control the interaction between DNA and gold nanoparticles via pH. The negatively charged phosphate backbone of ... -
Simple, Reversible, and Fast Modulation in Superwettability, Gradient, and Adsorption by Counterion Exchange on Self-Assembled Monolayer
( American Chemical Society , 2016 , Article)A simple fabrication method for preparation of surfaces able to switch from superhydrophobic to superhydrophilic state in a reversible and fast way is described. A self-assembled monolayer (SAM) consisting of quaternary ... -
Tailoring electrocatalytic properties of Pt nanoparticles grown on Ti3C2Tx MXene surface
( Electrochemical Society, Inc. , 2019 , Article)In this work, the spontaneous and NaBH4-induced reduction of chloroplatinic acid on the surface of Ti3C2TX MXene was investigated to synthesize a hybrid PtNP-decorated MXene nanomaterial (MX-Pt) with potential as hydrogen ... -
Ultrasensitive Ti3C2TX MXene/chitosan nanocomposite-based amperometric biosensor for detection of potential prostate cancer marker in urine samples
( MDPI AG , 2020 , Article)Two-dimensional layered nanomaterial Ti3C2TX (a member of the MXene family) was used to immobilise enzyme sarcosine oxidase to fabricate a nanostructured biosensor. The device was applied for detection of sarcosine, a ...
