Browsing by Author "Vasudevan, Karthick"
Now showing items 1-5 of 5
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Chapter Seven Exploring the effect of disease causing mutations in metal binding sites of human ARSA in metachromatic leukodystrophy
( Elsevier , 2024 , Book chapter)The arylsulfatase A (ARSA) gene is observed to be deficient in patients with metachromatic leukodystrophy (MLD), a type of lysosomal storage disease. MLD is a severe neurodegenerative disorder characterized by an autosomal ... -
Chapter Three Elucidating the mechanism of antimicrobial resistance in Mycobacterium tuberculosis using gene interaction networks
( Elsevier , 2023 , Book chapter)Antimicrobial resistance (AMR) in microorganisms is an urgent global health threat. AMR of Mycobacterium tuberculosis is associated with significant morbidity and mortality. It is of great importance to underpin the ... -
Identification of potential circadian genes and associated pathways in colorectal cancer progression and prognosis using microarray gene expression analysis
( Elsevier , 2023 , Book chapter)Colorectal cancer (CRC) is third cancer causing death in the world. CRC is associated with disrupting the circadian rhythm (CR), closely associating the CRC progression and the dysregulation of genes involved in the ... -
Integrated gene network analysis sheds light on understanding the progression of Osteosarcoma
( National library of medicine , 2023 , Article)Introduction: Osteosarcoma is a rare disorder among cancer, but the most frequently occurring among sarcomas in children and adolescents. It has been reported to possess the relapsing capability as well as accompanying ... -
Molecular characterization of circadian gene expression and its correlation with survival percentage in colorectal cancer patients
( Elsevier , 2023 , Book chapter)Colorectal cancer (CRC) is a form of cancer characterized by many symptoms and readily metastasizes to different organs in the body. Circadian rhythm is one of the many processes that is observed to be dysregulated in ...