Browsing by Author "Anupriya M, Geethakumari"

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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate

Geethakumari, Anupriya M; Sultana, Asfia; Fatima, Asma; Uddin, S M Nasir; Abdulhakim, Somaiya; Mohamed, Amera; Rahman, Samiha; Al-Buainain, Khaloud; Yassine, Hadi M; Khatib, Hebah A Al; Biswas, Kabir H... more authors ... less authors ( Elsevier , 2025 , Article)
Here, we report the engineering of a Bioluminescence Resonance Energy Transfer (BRET)-based SARS-CoV-2 main protease (Mpro) biosensor containing the Mpro N-terminal autocleavage sequence in tandem and a nanobody that shows ...