• Addressing bias in the definition of SARS-CoV-2 reinfection: implications for underestimation 

      Chemaitelly, Hiam; Ayoub, Houssein H.; Tang, Patrick; Yassine, Hadi M.; Al Thani, Asmaa A.; ... more authors ( Frontiers Media , 2024 , Article)
      Introduction: Reinfections are increasingly becoming a feature in the epidemiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, accurately defining reinfection poses methodological ...
    • All-cause and COVID-19 mortality in Qatar during the COVID-19 pandemic 

      Alnuaimi, Asma A.; Chemaitelly, Hiam; Semaan, Sandy; Almukdad, Sawsan; Al-Kanaani, Zaina; ... more authors ( BMJ Publishing Group , 2023 , Article)
      Objective To investigate all-cause mortality, COVID-19 mortality and all-cause non-COVID-19 mortality in Qatar during the COVID-19 pandemic. Methods A national, retrospective cohort analysis and national, matched, retrospective ...
    • Analytic comparison between three high-throughput commercial SARS-CoV-2 antibody assays reveals minor discrepancies in a high-incidence population 

      Nasrallah, Gheyath K; Dargham, Soha R; Shurrab, Farah; Al-Sadeq, Duaa W; Al-Jighefee, Hadeel; ... more authors ( Nature Research , 2021 , Article)
      Performance of three automated commercial serological IgG-based assays was investigated for assessing SARS-CoV-2 "ever" (past or current) infection in a population-based sample in a high exposure setting. PCR and serological ...
    • Antibiotic Prescription Patterns for Upper Respiratory Tract Infections in Outpatient Qatari Population in the Private Sector 

      Butt, Adeel Ajwad; Navasero, Cristina S.; Thomas, Bright; Al Marri, Salih; Al Katheeri, Huda; ... more authors ( Elsevier , 2016 , Article)
      Background: Antibiotic are often inappropriately prescribed for upper respiratory infections (URI) in the Western countries. Data on the proportion of inappropriate prescriptions are lacking from the Middle East and other ...
    • Assessing healthy vaccinee effect in COVID-19 vaccine effectiveness studies: a national cohort study in Qatar. 

      Chemaitelly, Hiam; Ayoub, Houssein H; Coyle, Peter; Tang, Patrick; Hasan, Mohammad R; ... more authors ( National Center for Biotechnology Information , 2025 , Article)
      This study investigated the presence of the healthy vaccinee effect-the imbalance in health status between vaccinated and unvaccinated individuals-in two rigorously conducted COVID-19 vaccine effectiveness studies involving ...
    • Assessing the performance of a serological point-of-care test in measuring detectable antibodies against SARS-CoV-2 

      El Kahlout, Reham Awni; Coyle, Peter V.; Dargham, Soha R.; Chemaitelly, Hiam; Kacem, Mohamed Ali Ben Hadj; ... more authors ( Public Library of Science , 2022 , Article)
      This study investigated the performance of a rapid point-of-care antibody test, the BioMedomics COVID-19 IgM/IgG Rapid Test, in comparison with a high-quality, validated, laboratory-based platform, the Roche Elecsys ...
    • Assessment of the Risk of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Reinfection in an Intense Reexposure Setting 

      Abu-Raddad, Laith J.; Chemaitelly, Hiam; Malek, Joel A.; Ahmed, Ayeda A.; Mohamoud, Yasmin A.; ... more authors ( NLM (Medline) , 2021 , Article)
      BACKGROUND: Risk of reinfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unknown. We assessed the risk and incidence rate of documented SARS-CoV-2 reinfection in a cohort of laboratory-confirmed ...
    • Association between COVID-19 vaccination and stroke: a nationwide case-control study in Qatar 

      Chemaitelly, Hiam; Akhtar, Naveed; Jerdi, Salman Al; Kamran, Saadat; Joseph, Sujatha; ... more authors ( Elsevier , 2024 , Article)
      Objective: This study investigated the association between Coronavirus Disease 2019 mRNA vaccination and stroke in Qatar. Methods: Between December 1, 2020, and April 11, 2023, a matched case-control study was conducted ...
    • Association of Prior SARS-CoV-2 Infection With Risk of Breakthrough Infection Following mRNA Vaccination in Qatar. 

      Abu-Raddad, Laith J; Chemaitelly, Hiam; Ayoub, Houssein H; Yassine, Hadi M; Benslimane, Fatiha M; ... more authors ( American Medical Association , 2021 , Article)
      The effect of prior SARS-CoV-2 infection on vaccine protection remains poorly understood. To assess protection from SARS-CoV-2 breakthrough infection after mRNA vaccination among persons with vs without prior SARS-CoV-2 ...
    • Associations of Vaccination and of Prior Infection with Positive PCR Test Results for SARS-CoV-2 in Airline Passengers Arriving in Qatar 

      Bertollini, Roberto; Chemaitelly, Hiam; Yassine, Hadi M.; Al-Thani, Mohamed H.; Al-Khal, Abdullatif; ... more authors ( American Medical Association , 2021 , Article)
      The SARS-CoV-2 pandemic has severely affected international travel. With efficacious COVID-19 vaccines available, Qatar implemented a pilot program between February 18 and April 26, 2021, to ease travel restrictions by ...
    • Bivalent mRNA-1273.214 vaccine effectiveness against SARS-CoV-2 omicron XBB* infections 

      Chemaitelly, Hiam; Ayoub, Houssein H.; AlMukdad, Sawsan; Faust, Jeremy S.; Tang, Patrick; ... more authors (2023 , Article)
      In October of 2022, Qatar introduced COVID-19 bivalent vaccination for persons ≥ 12 years using the 50-μg mRNA-1273.214 vaccine combining SARS-CoV-2 ancestral and omicron BA.1 strains.1 We estimated this vaccine’s effectiveness ...
    • BNT162b2 and mRNA-1273 COVID-19 vaccine effectiveness against the SARS-CoV-2 Delta variant in Qatar. 

      Tang, Patrick; Hasan, Mohammad R; Chemaitelly, Hiam; Yassine, Hadi M; Benslimane, Fatiha M; ... more authors ( Nature Researc , 2021 , Article)
      With the global expansion of the highly transmissible SARS-CoV-2 Delta (B.1.617.2) variant, we conducted a matched test-negative case-control study to assess the real-world effectiveness of COVID-19 messenger RNA vaccines ...
    • BNT162b2 antigen dose and SARS-CoV-2 omicron infection in adolescents 

      Chemaitelly, Hiam; Ayoub, Houssein H.; Coyle, Peter; Tang, Patrick; Yassine, Hadi M.; ... more authors ( Elsevier , 2023 , Other)
      COVID-19 vaccine antigen dose might affect protection against SARS-CoV-2 infection,1, 2 but direct evidence to quantify this effect is absent. We conducted a matched, retrospective, cohort study using a regression ...
    • BNT162b2 Versus mRNA-1273 Vaccines: Comparative Analysis of Long-Term Protection Against SARS-CoV-2 Infection and Severe COVID-19 in Qatar 

      Chemaitelly, Hiam; Ayoub, Houssein H; Coyle, Peter; Tang, Patrick; Hasan, Mohammad R; ... more authors ( Wiley , 2024 , Article)
      Background: This study provides a head-to-head comparison of the protection provided by the BNT162b2 and mRNA-1273 vaccines against SARS-CoV-2 infection and against severe COVID-19, covering primary series and third ...
    • Characterizing the Qatar advanced-phase SARS-CoV-2 epidemic 

      Abu-Raddad, Laith J.; Chemaitelly, Hiam; Ayoub, Houssein H.; Al Kanaani, Zaina; Al Khal, Abdullatif; ... more authors ( springer nature , 2021 , Article)
      The overarching objective of this study was to provide the descriptive epidemiology of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic in Qatar by addressing specific research questions through a ...
    • Comparative effectiveness of one versus two doses of COVID-19 vaccines in Qatar: Evidence of converging protection over time 

      Hiam, Chemaitelly; Ayoub, Houssein H.; Coyle, Peter; Tang, Patrick; Hasan, Mohammad R.; ... more authors ( Elsevier , 2025 , Article)
      BackgroundSupply constraints during the coronavirus disease 2019 (COVID-19) pandemic led to vaccination strategies that prioritized first-dose coverage. To evaluate the merit of this approach, this study compared the ...
    • Coronavirus Disease 2019 Disease Severity in Children Infected With the Omicron Variant 

      Butt, A.A.; Butt, Adeel A.; Dargham, Soha R.; Loka, Srusvin; Shaik, Riyazuddin M.; ... more authors ( NLM (Medline) , 2022 , Article)
      SHORT SUMMARY: Severe acute respiratory syndrome coronavirus 2 infection from the Omicron variant in children/adolescents is less severe than infection from the Delta variant. Those 6 to <18 years also have less severe ...
    • COVID-19 Disease Severity in Persons Infected with Omicron BA.1 and BA.2 Sublineages and Association with Vaccination Status 

      Butt, Adeel A.; Dargham, Soha R.; Coyle, Peter; Yassine, Hadi M.; Al-Khal, Abdullatif; ... more authors ( American Medical Association , 2022 , Article)
      Infection with the SARS-CoV-2 Omicron variant is associated with less severe disease compared with the Delta variant.1-3 Two main Omicron sublineages—BA.1 and BA.2—have variable geographic distribution. In Qatar, BA.1 was ...
    • COVID-19 risk score as a public health tool to guide targeted testing: A demonstration study in Qatar 

      J. Abu-Raddad, Laith; Dargham, Soha; Chemaitelly, Hiam; Coyle, Peter; Al Kanaani, Zaina; ... more authors ( Public Library of Science , 2022 , Article)
      We developed a Coronavirus Disease 2019 (COVID-19) risk score to guide targeted RTPCR testing in Qatar. The Qatar national COVID-19 testing database, encompassing a total of 2,688,232 RT-PCR tests conducted between February ...
    • COVID-19 vaccine hesitancy and attitudes in Qatar: A national cross-sectional survey of a migrant-majority population 

      Alabdulla, Majid; Reagu, Shuja Mohd; Al-Khal, Abdullatif; Elzain, Marwa; Jones, Roland M. ( Blackwell Publishing Ltd , 2021 , Article)
      Background: Vaccine hesitancy is a global threat undermining control of preventable infections. Emerging evidence suggests that hesitancy to COVID-19 vaccination varies globally. Qatar has a unique population with around ...