Browsing by Author "Ashour, Hayam M.A."
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Novel 1,5-diphenyl-6-substituted 1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones induced apoptosis in RKO colon cancer cells
Malki, Ahmed; Ashour, Hayam M.A.; Elbayaa, Rasha Y.; Issa, Doaa A. E.; Aziz, Hassan A.; Chen, Xiaozhuo... more authors ... less authors ( Taylor & Francis , 2015 , Article)Novel 1,5-diphenyl-6-substituted-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-ones were synthesized and characterized. All compounds were screened for their anti-proliferative activities in five different cancer cell lines. The results ... -
Novel thiosemicarbazides induced apoptosis in human MCF-7 breast cancer cells via JNK signaling
Malki, Ahmed; Elbayaa, Rasha Y.; Ashour, Hayam M.A.; Loffredo, Christopher A.; Youssef, Amal M. ( Taylor & Francis , 2015 , Article)In this study, novel thiosemicarbazides and 1,3,4-oxadiazoles were synthesized and evaluated for their anticancer effects on human MCF-7 breast cancer cell lines. Among the synthesized derivatives studied, compound ...