Browsing by Author "Elhissi, A."
Now showing items 1-7 of 7
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Ethanol-based proliposome delivery systems of paclitaxel for in vitro application against brain cancer cells
( Taylor and Francis Ltd , 2018 , Article)In this study the anticancer activity of paclitaxel-loaded nano-liposomes on glioma cell lines was investigated. Soya phosphatidylcholine:cholesterol (SPC:Chol), hydrogenated soya phosphatidylcholine:cholesterol (HSPC:Chol) ... -
Liposome Delivery Systems for Inhalation: A Critical Review Highlighting Formulation Issues and Anticancer Applications
( S. Karger AG , 2016 , Conference Paper)This is a critical review on research conducted in the field of pulmonary delivery of liposomes. Issues relating to the mechanism of nebulisation and liposome composition were appraised and correlated with literature reports ... -
Preparation and characterization of letrozole-loaded poly(d,l-lactide) nanoparticles for drug delivery in breast cancer therapy
( Taylor and Francis Ltd , 2019 , Article)Letrozole (LTZ), an aromatase inhibitor used for the treatment of hormonally-positive breast cancer in postmenopausal women, has poor water solubility, rapid metabolism, and a range of side effects. In this study, polymer-based ... -
Preparation and optimization of monodisperse polymeric microparticles using modified vibrating orifice aerosol generator for controlled delivery of letrozole in breast cancer therapy
( Taylor and Francis Ltd. , 2018 , Article)Letrozole (LTZ) is effective for the treatment of hormone-receptor-positive breast cancer in postmenopausal women. In this work, and for the first time, using vibrating orifice aerosol generator (VOAG) technology, monodisperse ... -
Proliposome tablets manufactured using a slurry-driven lipid-enriched powders: Development, characterization and stability evaluation
( Elsevier B.V. , 2018 , Article)Proliposome powders were prepared via a slurry method using sorbitol or D-mannitol as carbohydrate carriers in 1:10 or 1:15 w/w lipid phase to carrier ratios. Soya phosphatidylcholine (SPC) and cholesterol were employed ... -
Recent advances in applications of active constituents of selected medicinal plants of dhofar, sultanate of oman
( Innovare Academics Sciences Pvt. Ltd , 2018 , Article Review)The Dhofar region of Oman is extremely opulent in plant biodiversity in comparison to other parts of the country. Most of the cultivated, medicinal and wild plants of the region are available in the mountainous side and ... -
Taxane formulations: From plant to clinic
( Springer International Publishing , 2017 , Book chapter)Taxanes including paclitaxel and docetaxel are highly active against many types of cancers. The main obstacle with developing delivery systems of taxanes is their poor water solubility. In this chapter, taxanes were reviewed ...
