Browsing by Author "Nair, Rajesh Sreedharan"
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An evaluation of tocotrienol ethosomes for transdermal delivery using Strat-M® membrane and excised human skin
Nair, Rajesh Sreedharan; Billa, Nashiru; Leong, Chee Onn; Morris, Andrew P. ( Taylor and Francis Ltd. , 2021 , Article)Tocotrienol (TRF) ethosomes were developed and evaluated in vitro for potential transdermal delivery against melanoma. The optimised TRF ethosomal size ranged between 64.9 ± 2.2 nm to 79.6 ± 3.9 nm and zeta potential (ZP) ... -
Orally Administered Amphotericin B Nanoformulations: Physical Properties of Nanoparticle Carriers on Bioavailability and Clinical Relevance
Fairuz, Shadreen; Nair, Rajesh Sreedharan; Billa, Nashiru ( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)Amphotericin B is an effective polyene antifungal considered as a “gold standard” in the management of fungal infections. Currently, it is administered mainly by IV due to poor aqueous solubility, which precludes its ... -
A Validated Reverse-Phase High Performance Liquid Chromatography (RP-HPLC) Method for the Quantification of Gamma-Tocotrienol in Tocotrienol Rich Fractions of Crude Palm Oil
Nair, Rajesh Sreedharan; Billa, Nashiru; Morris, Andrew ( Bentham , 2021 , Article)Background: Palm oil and its constituents have wide applications in food, cosmet-ics and pharmaceutical industries. The tocotrienol-rich fractions of crude palm oil have drawn greater research interest in recent years due ...