Browsing by Author "Thompson, I. Richard"

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Combined Noncoding RNA-mRNA Regulomics Signature in Reprogramming and Pluripotency in iPSCs

Salloum-Asfar, Salam; Abdulla, Sara A.; Taha, Rowaida Z.; Thompson, I. Richard; Emara, Mohamed M. ( Multidisciplinary Digital Publishing Institute (MDPI) , 2022 , Article)
Somatic cells are reprogrammed with reprogramming factors to generate induced pluripotent stem cells (iPSCs), offering a promising future for disease modeling and treatment by overcoming the limitations of embryonic stem ...
Hyperosmotic Stress Induces a Specific Pattern for Stress Granule Formation in Human-Induced Pluripotent Stem Cells

Salloum-Asfar, Salam; Engelke, Rudolf; Mousa, Hanaa; Goswami, Neha; Thompson, I. Richard; ... more authors ( Hindawi , 2021 , Article)
Stress granules (SGs) are assemblies of selective messenger RNAs (mRNAs), translation factors, and RNA-binding proteins in small untranslated messenger ribonucleoprotein (mRNP) complexes in the cytoplasm. Evidence indicates ...
Inter-Versus Intra-Host Sequence Diversity of pH1N1 and Associated Clinical Outcomes

Al Khatib, Hebah A.; Al Maslamani, , Muna A.; V. Coyle, Peter; Thompson, I. Richard Thompson; A. Farag, Elmoubasher; ... more authors ( MDPI , 2020 , Article)
The diversity of RNA viruses dictates their evolution in a particular host, community or environment. Here, we reported within- and between-host pH1N1virus diversity at consensus and sub-consensus levels over a three-year ...