• Aberrant DNA methylation of PTPRG as one possible mechanism of its under-expression in CML patients in the State of Qatar 

      Ismail, Mohamed A; Samara, Muthanna; Al Sayab, Ali; Alsharshani, Mohamed; Yassin, Mohamed A; ... more authors ( Wiley Open Access , 2020 , Article)
      Several studies showed that aberrant DNA methylation is involved in leukemia and cancer pathogenesis. Protein tyrosine phosphatase receptor gamma (PTPRG) expression is a natural inhibitory mechanism that is downregulated ...
    • Association of single nucleotide polymorphisms with dyslipidemia and risk of metabolic disorders in the State of Qatar 

      Al-Sharshani, Dalal; Velayutham, Dinesh; Samara, Muthanna; Gazal, Reham; Al Haj Zen, Ayman; ... more authors ( Wiley-Blackwell , 2023 , Article)
      Background: Dyslipidemia is recognized as one of the risk factors of cardiovascular diseases (CVDs), type 2 diabetes mellitus (T2DM), and non-alcoholic fatty liver disease (NAFLD). Objective: The study aimed to investigate ...
    • Management of chronic myeloid leukaemia: current treatment options, challenges, and future strategies. 

      Younes, Salma; Ismail, Mohamed A; Al-Jurf, Rana; Ziyada, Ayah; Nasrallah, Gheyath K; ... more authors ( taylor and francis online , 2023 , Article)
      Small molecule therapy is a critical component of targeted anticancer treatment, with tyrosine kinase inhibitors (TKIs) being the first compounds to treat the clonal Chronic Myelogenous Leukaemia (CML) translocation t ...
    • Maternal and neonatal risks and outcomes after bariatric surgery: a comparative population based study across BMI categories in Qatar. 

      Al-Dewik, Nader I; Samara, Muthanna; Mahmah, Adel; Al-Dewik, Aseel; Abou Nahia, Seba; ... more authors ( Springer Nature , 2024 , Article)
      The impact of Bariatric Surgery (BS) on maternal and neonatal outcomes among pregnant women is not fully understood, especially in comparison to different weight categories. The primary aim of this study is to assess the ...