• Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019 

      Zuniga, Yves Miel H.; Zumla, Alimuddin; Zuhlke, Liesl J.; Zoladl, Mohammad; Ziaeian, Boback; ... more authors ( Nature Publishing Group , 2025 , Article)
      Chronic care manages long-term, progressive conditions, while acute care addresses short-term conditions. Chronic conditions increasingly strain health systems, which are often unprepared for these demands. This study ...
    • Global age-sex-specific all-cause mortality and life expectancy estimates for 204 countries and territories and 660 subnational locations, 1950–2023: a demographic analysis for the Global Burden of Disease Study 2023 

      Austin E, Schumacher; Zheng, Peng; Barber, Ryan M; A, Bhoomadevi; Aalipour, Mohammad Amin; ... more authors ( Elsevier , 2025 , fla  &   Article)
      BackgroundComprehensive, comparable, and timely estimates of demographic metrics—including life expectancy and age-specific mortality—are essential for evaluating, understanding, and addressing trends in population health. ...
    • Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 

      Michael, Brauer; Roth, Gregory A; Aravkin, Aleksandr Y; Zheng, Peng; Abate, Kalkidan Hassen; ... more authors ( Elsevier Ltd. , 2024 , Article)
      Background: Understanding the health consequences associated with exposure to risk factors is necessary to inform public health policy and practice. To systematically quantify the contributions of risk factor exposures to ...
    • Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 

      Natalia V, Bhattacharjee; Schumacher, Austin E; Aali, Amirali; Abate, Yohannes Habtegiorgis; Abbasgholizadeh, Rouzbeh; ... more authors ( Elsevier , 2024 , Article)
      Background Accurate assessments of current and future fertility—including overall trends and changing population age structures across countries and regions—are essential to help plan for the profound social, economic, ...
    • Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 

      Alize J, Ferrari; Santomauro, Damian Francesco; Aali, Amirali; Abate, Yohannes Habtegiorgis; Abbafati, Cristiana; ... more authors ( Elsevier , 2024 , Article)
      Background Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury ...
    • Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analysis for the Global Burden of Disease Study 2021 

      Hmwe Hmwe, Kyu; Vongpradith, Avina; Dominguez, Regina-Mae Villanueva; Ma, Jianing; Albertson, Samuel B; ... more authors ( Elsevier , 2024 , Article)
      BackgroundDiarrhoeal diseases claim more than 1 million lives annually and are a leading cause of death in children younger than 5 years. Comprehensive global estimates of the diarrhoeal disease burden for specific age ...
    • Global, regional, and national burden of Chagas disease, 1990–2023: a systematic analysis for the Global Burden of Disease Study 2023 

      Cousin, Ewerton; Nascimento, Bruno Ramos; Whisnant, Joanna L; Zimsen, Stephanie R M; Harris, Ashley Ann; ... more authors ( Elsevier , 2025 , Article)
      BackgroundChagas disease is a neglected tropical disease caused by the protozoan Trypanosoma cruzi, primarily transmitted by infected bugs, but also through contaminated food, transfusions, congenital transmission, and ...
    • Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 

      Jaimie D, Steinmetz; Seeher, Katrin Maria; Schiess, Nicoline; Nichols, Emma; Cao, Bochen; ... more authors ( Elsevier , 2024 , Article)
      Background Disorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous ...
    • Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021 

      Austin, Carter; Zhang, Meixin; Tram, Khai Hoan; Walters, Magdalene K; Jahagirdar, Deepa; ... more authors ( Elsevier , 2024 , Article)
      BackgroundAs set out in Sustainable Development Goal 3.3, the target date for ending the HIV epidemic as a public health threat is 2030. Therefore, there is a crucial need to evaluate current epidemiological trends and ...
    • Global, regional, and national burden of upper respiratory infections and otitis media, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021 

      Sirota, Sarah Brooke; Doxey, Matthew C; Dominguez, Regina-Mae Villanueva; Bender, Rose Grace; Vongpradith, Avina; ... more authors ( Elsevier Ltd. , 2024 , Article)
      Background: Upper respiratory infections (URIs) are the leading cause of acute disease incidence worldwide and contribute to a substantial health-care burden. Although acute otitis media is a common complication of URIs, ...