Browsing by Author "Gorin, Yves"

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    • Sestrin2 as a Novel Biomarker and Therapeutic Target for Various Diseases 

      Pasha, Mazhar; Eid, Ali H.; Eid, Assaad A.; Gorin, Yves; Munusamy, Shankar ( Hindawi , 2017 , Article)
      Sestrin2 (SESN2), a highly conserved stress-inducible metabolic protein, is known to repress reactive oxygen species (ROS) and provide cytoprotection against various noxious stimuli including genotoxic and oxidative stress, ...

    • The protective role of Sestrin2 in high fat diet-induced nephropathy 

      Agouni, Abdelali; Lee, Duck Y; Eid, Assaad A; Gorin, Yves; Sharma, Kumar ( Qatar University Press , 2020 , Poster)
      Introduction: Obesity is a major risk factor for type-2 diabetes predisposing patients to diabetic nephropathy (DN), the leading cause of end-stage renal failure. Glomerular injury is a prominent pathological feature of ...