تصفح حسب المؤلف "Schmidt, Frank"
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Hyperosmotic Stress Induces a Specific Pattern for Stress Granule Formation in Human-Induced Pluripotent Stem Cells
Salloum-Asfar, Salam; Engelke, Rudolf; Mousa, Hanaa; Goswami, Neha; Thompson, I. Richard; Palangi, Freshteh; Kamal, Kamal; Al-Noubi, Muna N.; Schmidt, Frank; Abdulla, Sara A.; Emara, Mohamed M.... more authors ... less authors ( Hindawi , 2021 , Article)Stress granules (SGs) are assemblies of selective messenger RNAs (mRNAs), translation factors, and RNA-binding proteins in small untranslated messenger ribonucleoprotein (mRNP) complexes in the cytoplasm. Evidence indicates ... -
SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways.
Majeed, Yasser; Halabi, Najeeb; Madani, Aisha Y; Engelke, Rudolf; Bhagwat, Aditya M; Abdesselem, Houari; Agha, Maha V; Vakayil, Muneera; Courjaret, Raphael; Goswami, Neha; Hamidane, Hisham Ben; Elrayess, Mohamed A; Rafii, Arash; Graumann, Johannes; Schmidt, Frank; Mazloum, Nayef A... more authors ... less authors ( Nature Research , 2021 , Article)The NAD-dependent deacetylase SIRT1 controls key metabolic functions by deacetylating target proteins and strategies that promote SIRT1 function such as SIRT1 overexpression or NAD boosters alleviate metabolic complications. ...