Browsing by Author "Chaffin, Mark"

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Genome-wide polygenic score, clinical risk factors, and long-term trajectories of coronary artery disease

Hindy, George; Aragam, Krishna G.; Ng, Kenney; Chaffin, Mark; Lotta, Luca A.; Baras, Aris; Drake, Isabel; Orho-Melander, Marju; Melander, Olle; Kathiresan, Sekar; Khera, Amit V.... more authors ... less authors ( American Heart Association , 2020 , Article)
OBJECTIVE: To determine the relationship of a genome-wide polygenic score for coronary artery disease (GPSCAD) with lifetime trajectories of CAD risk, directly compare its predictive capacity to traditional risk factors, ...