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السجلات المعروضة 20824 -- 20843 من 50793
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Protective Effect of Previous SARS-CoV-2 Infection against Omicron BA.4 and BA.5 Subvariants.
( Massachusetts Medical Society , 2022 , Article)The BA.4 and BA.5 subvariants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B.1.1.529 (omicron) variant have shown the capacity of escaping from neutralizing antibodies.1 These subvariants had an ... -
Protective effects of ethyl acetate fraction of Lawsonia inermis fruits extract against carbon tetrachloride-induced oxidative damage in rat liver
( SAGE Publications , 2013 , Article)This study aimed to investigate the antioxidant properties of different fractions obtained from the fruits of Lawsonia inermis, a widely used medicinal plant, against carbon tetrachloride (CCl4)-induced oxidative stress ... -
PROTECTIVE EFFECTS OF METFORMIN IN AN IN VITRO MODEL OF PROTEINURIC KIDNEY DISEASE
(2017 , Master Thesis)Albuminuria, a hallmark of chronic kidney disease (CKD), plays a crucial role in the etiology of CKD. High albumin levels are thought to induce endoplasmic reticulum (ER) stress and activate the AKT pathway, and lead to ... -
Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling
( American Society for Biochemistry and Molecular Biology Inc. , 2019 , Article)Epigenetic regulation by the type II protein arginine methyltransferase, PRMT5, plays an essential role in the control of cancer cell proliferation and tumorigenesis. In this report, we investigate the relationship between ... -
Protein expression profiling identifies key proteins and pathways involved in growth inhibitory effects exerted by guggulsterone in human colorectal cancer cells
( MDPI AG , 2019 , Article)Colorectal cancer (CRC) is a leading killer cancer worldwide and one of the most common malignancies with increasing incidences of mortality. Guggulsterone (GS) is a plant sterol used for treatment of various ailments such ... -
Protein Glycation in Plants-An Under-Researched Field with Much Still to Discover.
( MDPI , 2020 , Article)Recent research has identified glycation as a non-enzymatic post-translational modification of proteins in plants with a potential contributory role to the functional impairment of the plant proteome. Reducing sugars with ... -
Protein glycation – biomarkers of metabolic dysfunction and early-stage decline in health in the era of precision medicine
( Elsevier , 2021 , Article)Protein glycation provides a biomarker in widespread clinical use, glycated hemoglobin HbA1c (A1C). It is a biomarker for diagnosis of diabetes and prediabetes and of medium-term glycemic control in patients with established ... -
Protein intake among patients with diabetes is linked poor glycemic control
( Qatar University Press , 2020 , Poster)Background: Nutrition therapy is considered a key component of diabetes management. High-protein diets are recently gaining more popularity. Knowledge regarding the potential glycemic effect of protein in people with type ... -
Protein Intake Among Patients with Insulin-Treated Diabetes is Linked to Poor Glycemic Control: Findings of NHANES Data
( Dove Press , 2022 , Article)Background: Nutrition therapy is considered a key component of diabetes management. Recently, high-protein diets have gained in popularity. Understanding the glycemic effect of dietary protein among patients with diabetes ... -
Protein Tyrosine Phosphatase (PTP) 1B Inhibition Improves Endoplasmic Reticulum Stress-Induced Apoptosis and Impaired Angiogenic Response in Endothelial Cells
( Qatar University Press , 2021 , Poster)Insulin is not only important for glucose homeostasis, but also plays a critical role in the activation of endothelial nitric oxide synthase (eNOS) to synthesize nitric oxide (NO) and keeping the endothelium functional. ... -
Protein tyrosine phosphatase 1B inhibition improves endoplasmic reticulum stress-impaired endothelial cell angiogenic response: A critical role for cell survival
( Spandidos publications , 2021 , Article)Endoplasmic reticulum (ER) stress contributes to endothelial dysfunction, which is the initial step in atherogenesis. Blockade of protein tyrosine phosphatase (PTP)1B, a negative regulator of insulin receptors that is ... -
Proteins of cottonseed (gossypium barbadense) .• extraction and characterization by electrophoresis
( Qatar University , 1995 , Article)The seed proteins of cotton (Gossypium barbadense) were quantitavely and qualitavely investigated. The qualitative study was carried out using different electrophoretic techniques ((PAGE, SDS-PAGE, Poro-PAGE, SDS-Poro-PAGE, ... -
Proteome changes in autosomal recessive primary microcephaly
( Wiley , 2022 , Article)Background/aim: : Autosomal recessive primary microcephaly (MCPH) is a rare and genetically heterogeneous group of disorders characterized by intellectual disability and microcephaly at birth, classically without further ... -
Proteomic analysis of T. qataranse exposed to lead (Pb) stress reveal new proteins with potential roles in Pb tolerance and detoxification mechanism
( Frontiers Media , 2022 , Article)Soil lead (Pb) contamination is one of the environmental problems facing the modern world. Sources of Pb in soil include industrial activities such as mining and smelting processes, agricultural activities such as application ... -
Proteomic analysis of the endometrium during early pregnancy in the domestic pig.
( CSIRO Publishing , 2017 , Article)Reproductive processes in domestic pigs have been studied extensively. Pigs are one of the main sources of meat for human consumption and are an established model for investigations into mammalian, including human, ... -
Proteomic insight towards key modulating proteins regulated by the aryl hydrocarbon receptor involved in ovarian carcinogenesis and chemoresistance
( Elsevier , 2024 , Article)Gynecological malignancies pose a severe threat to female lives. Ovarian cancer (OC), the most lethal gynecological malignancy, is clinically presented with chemoresistance and a higher relapse rate. Several studies have ... -
Proteomic profile alterations in porcine conceptuses during early stages of development
( Elsevier , 2021 , Article)The dynamic embryo development during the early stages of gestation requires precise molecular changes, including proteomic ones. We aimed to find unique proteins for porcine conceptuses specifically during the peri-implantation ... -
Proteomic profile in congenital microcephaly
( Qatar University Press , 2021 , Poster)Autosomal recessive primary microcephaly (MCPH) consists of a group of disorders characterized by microcephaly and intellectual disability. This study is essential to complement previous findings of MCPH as it helps clarify ... -
Proteomic Profiling of Diffuse Large B-Cell Lymphomas
( Karger Publishers , 2018 , Article)The aim of this study was to identify differences in proteome profiles of diffuse large B-cell lymphoma (DLBCL) of nongerminal center (non-GC) versus GC type in the search for new markers and drug targets. Six DLBCL, with ... -
Proteomic Profiling of Small-Cell Lung Cancer: A Systematic Review
( Multidisciplinary Digital Publishing Institute (MDPI) , 2023 , Article)The accurate diagnosis of small-cell lung cancer (SCLC) is crucial, as treatment strategies differ from those of other lung cancers. This systematic review aims to identify proteins differentially expressed in SCLC compared ...
