Browsing by Subject "Obesity"
Now showing items 61-74 of 74
-
Progressive circuit resistance training improves inflammatory biomarkers and insulin resistance in obese men
( Elsevier Inc. , 2019 , Article)Circuit resistance training (CRT) is a time-efficient exercise modality for improving skeletal muscle and cardiovascular fitness. But the beneficial role of CRT in obese individuals is still not well understood. This study ... -
Promoter–enhancer looping at the PPARγ2 locus during adipogenic differentiation requires the Prmt5 methyltransferase
( Oxford University Press , 2016 , Article)PPARγ2 is a critical lineage-determining transcription factor that is essential for adipogenic differentiation. Here we report characterization of the three-dimensional structure of the PPARγ2 locus after the onset of ... -
The Qatar Biobank: background and methods
( BioMed Central , 2015 , Article)Background: The Qatar Biobank aims to collect extensive lifestyle, clinical, and biological information from up to 60,000 men and women Qatari nationals and long-term residents (individuals living in the country for ≥15 ... -
The Regulation of BRN3B in Adipocytes by Glucose and Insulin
(2014 , Master Thesis)Obesity is the inappropriate accumulation of excess fat stored in the adipocytes of the adipose tissue. Understanding the molecular mechanisms that regulate the process of the preadipocyte to adipocyte conversion, adipogenesis, ... -
Reversal of insulin resistance in overweight and obese subjects by trans-resveratrol and hesperetin combination—link to dysglycemia, blood pressure, dyslipidemia, and low-grade inflammation
( Multidisciplinary Digital Publishing Institute (MDPI) , 2021 , Article)The dietary supplement, trans-resveratrol and hesperetin combination (tRES-HESP), induces expression of glyoxalase 1, countering the accumulation of reactive dicarbonyl glycating agent, methylglyoxal (MG), in overweight ... -
Rivaroxaban Pharmacokinetics in Obese Subjects: A Systematic Review
( Springer Nature , 2022 , Article)Venous thromboembolism (VTE) is a leading cause of morbidity and mortality globally. The direct oral anticoagulants, including rivaroxaban, are relatively novel therapeutic options in the treatment and prevention of VTE. ... -
Role of the Gastrointestinal Tract Microbiome in the Pathophysiology of Diabetes Mellitus.
( Hindawi Publishing Corporation , 2017 , Article)The incidence of diabetes mellitus is rapidly increasing throughout the world. Although the exact cause of the disease is not fully clear, perhaps, genetics, ethnic origin, obesity, age, and lifestyle are considered as few ... -
Sleep problems in adolescence and overweight/obesity in young adults: is there a causal link?
( Elsevier , 2018 , Article)This study aims to explore if there is a causal association between adolescence sleep problems and overweight/obesity (Ow/Ob) in young adults. Youth self-reports were used to explore if adolescence (mean age 13.90 years, ... -
The effect of subsidies on healthful consumption: Systematic review and data synthesis
( Qatar University Press , 2020 , Poster)Background: Prevalence of obesity and overweight has risen to the level of an epidemic. Health policy makers are seeking evidence-based solutions to this problem. This study reviews evidence on the subsidization of healthy ... -
The protective role of Sestrin2 in high fat diet-induced nephropathy
( Qatar University Press , 2020 , Poster)Introduction: Obesity is a major risk factor for type-2 diabetes predisposing patients to diabetic nephropathy (DN), the leading cause of end-stage renal failure. Glomerular injury is a prominent pathological feature of ... -
The Role of GATA3 in Adipogenesis & Insulin Resistance
( Qatar University Press , 2020 , Poster)Background: Impaired adipogenesis plays an important role in the development of obesity-associated insulin resistance and type 2 diabetes. Adipose tissue inflammation is a crucial mediator of this process. In hyperglycemia, ... -
Topiramate monotherapy for weight reduction in patients with type 2 diabetes mellitus: A systematic review and meta-analysis
( Elsevier Ireland Ltd , 2016 , Article)Aims: To conduct a systematic review with meta-analysis to determine the efficacy and safety of topiramate as monotherapy for weight reduction in patients with type 2 diabetes mellitus. Methods: We searched MEDLINE, Embase, ... -
Unique associations of the Job Demand-Control-Support model subscales with leisure-time physical activity and dietary energy intake
( National Institute of Occupational Safety and Health , 2018 , Article)Leisure-time physical activity (LTPA) and dietary energy intake are two important health behaviours, which at too low or high levels respectively, are associated with overweight and obesity. This study explores associations ... -
Vascular Endothelial Dysfunction as the Mechanism for Development of Obesity
(2018 , Master Thesis)Obesity is one of the major public health issues in the world with a rapid increase in its prevalence. According to the last public health report from supreme public health in Qatar in 2012, 71.8 % of the women were ...