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Now showing items 11463-11482 of 48217
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Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer
( BMJ Publishing Group , 2020 , Article)Introduction Patients with diabetes have increased risk of periodontal disease, with increased risk of weakening of periodontal ligament and tooth loss. Periodontal ligament is produced and maintained by periodontal ligament ... -
Glycomic and Glycoproteomic Techniques in Neurodegenerative Disorders and Neurotrauma: Towards Personalized Markers
( MDPI , 2022 , Article Review)The proteome represents all the proteins expressed by a genome, a cell, a tissue, or an organism at any given time under defined physiological or pathological circumstances. Proteomic analysis has provided unparalleled ... -
Glycomics meets artificial intelligence – Potential of glycan analysis for identification of seropositive and seronegative rheumatoid arthritis patients revealed
( Elsevier B.V. , 2018 , Article)In this study, one hundred serum samples from healthy people and patients with rheumatoid arthritis (RA) were analyzed. Standard immunoassays for detection of 10 different RA markers and analysis of glycan markers on ... -
Glycomics of prostate cancer: updates
( Taylor and Francis Ltd , 2019 , Article)Introduction: Prostate cancer (PCa) is a life-threatening disease affecting millions of men. The current best PCa biomarker (level of prostate-specific antigen in serum) lacks specificity for PCa diagnostics and this is ... -
Glycoprofiling as a novel tool in serological assays of systemic sclerosis: A comparative study with three bioanalytical methods
( Elsevier , 2015 , Article)Systemic sclerosis (SSc) is an autoimmune disease seriously affecting patient’s quality of life. The heterogeneity of the disease also means that identification and subsequent validation of biomarkers of the disease is ... -
Glycoprofiling of cancer biomarkers: Label-free electrochemical lectin-based biosensors
( De Gruyter , 2015 , Article)Glycosylation of biomolecules is one of the most prevalent post- and co-translational modification in a human body, with more than half of all human proteins being glycosylated. Malignant transformation of cells influences ... -
Glycoside-based niosomal nanocarrier for enhanced in-vivo performance of Cefixime
( Elsevier B.V. , 2016 , Article)This study aimed to evaluate the potential of a novel glycoside non-ionic surfactant synthesized and characterized in our laboratory for increased oral bioavailability of Cefixime. The surfactant was synthesized by simple ... -
Glycosides of Heterocycles: A Direct Route to 1-(β-D-Glycopyranosyl)pyridinethione Nucleosides
( WILEY-VCH Verlag , 1994 , Article)A novel synthesis of 1-(β-d-glycopyranosyl)pyridinethione nucleosides 6 utilizing pyridine-2(1H)-thiones 3 and α-halogeno sugars 4 as starting components is reported. -
Glycosylation is a novel TGF?1-independent post-translational modification of Smad2
( Elsevier B.V. , 2019 , Article)Smad2 is a crucial component of intracellular signaling by transforming growth factor-? (TGF?). Here we describe that Smad2 is glycosylated, which is a novel for Smad2 post-translational modification. We showed that the ... -
Goal programming for financial portfolio management: a state-of-the-art review
( Springer Nature , 2017 , Article)Over the last decades, the Goal Programming (GP) model has been applied to financial portfolio management and/or selection problem in decision-making contexts where several conflicting and incommensurable objectives are ... -
A Goal Programming Model for Capital Rationing with a Linear Cash Fluctuations Measure
( Qatar University , 1997 , Article) -
Goal programming model for management accounting and auditing: a new typology
( Springer New York LLC , 2017 , Article)In practice, generally the accountants are facing complex decision-making situations where they aggregate simultaneously several conflicting and incommensurable factors (dimensions). They look for the decision of the best ... -
Going meta: Bringing together an understanding of metadiscourse with students' metalinguistic understanding
( Cambridge University Press , 2023 , Other)The impetus behind this seminar series was a study (Writing the Future) funded by the Qatar National Research Foundation and conducted collaboratively by the University of Exeter and Qatar University. The study involved a ... -
Gold Nanoparticle-Based Platforms for Diagnosis and Treatment of Myocardial Infarction
( American Chemical Society , 2020 , Article)In recent years, an increasing rate of mortality due to myocardial infarction (MI) has led to the development of nanobased platforms, especially gold nanoparticles (AuNPs), as promising nanomaterials for diagnosis and ... -
GOLD NANOPARTICLES-BASED ASSAYS FOR DIRECT AND COST EFFECTIVE DETECTION OF CLOSTRIDIUM DIFFICILE IN QATAR
(2015 , Master Thesis)Background Clostridium difficile Infection (CDI) is one of the common health problems worldwide. Prevention techniques require fast and precise detection with high sensitivity. Conventional diagnostic methods are ... -
Gold nanozyme: Biosensing and therapeutic activities
( Elsevier Ltd , 2020 , Article)The utilization of AuNPs in therapeutic applications has been accelerated by discovering their catalytic activity consistent with the activity of natural enzymes. However, to reduce unwanted activities, it is imperative ...
