Browsing by Author "Eid, Ali H."
Now showing items 21-40 of 136
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Carnosol Is a Novel Inhibitor of p300 Acetyltransferase in Breast Cancer
Alsamri, Halima; Hasasna, Hussain El; Baby, Bincy; Alneyadi, Aysha; Dhaheri, Yusra Al; Ayoub, Mohammed Akli; Eid, Ali H.; Vijayan, Ranjit; Iratni, Rabah... more authors ... less authors ( Frontiers Media S.A. , 2021 , Article)Carnosol, a natural polyphenol abundant in edible plants such as sage, rosemary, and oregano, has shown promising anticancer activity against various types of cancers. Nonetheless, very little is known about its molecular ... -
Chemical Analysis and Investigation of Biological Effects of Salvia officinalis Essential Oils at Three Phenological Stages
Assaggaf, Hamza M.; Naceiri Mrabti, Hanae; Rajab, Bodour S.; Attar, Ammar A.; Alyamani, Reema A.; Hamed, Munerah; El Omari, Nasreddine; El Menyiy, Naoual; Hazzoumi, Zakaria; Benali, Taoufiq; Al-Mijalli, Samiah Hamad; Zengin, Gokhan; AlDhaheri, Yusra; Eid, Ali H.; Bouyahya, Abdelhakim... more authors ... less authors ( MDPI , 2022 , Article)Salvia officinalis is a medicinal plant used to treat some diseases, including microbial infections and diabetes. Different studies showed the biological and pharmacological properties of this species. The aim of this study ... -
Colorectal and Prostate Cancer Risk in Diabetes: Metformin, an Actor behind the Scene
Anwar, M. Akhtar; Kheir, Wassim Abou; Eid, Stephanie; Fares, Joanna; Liu, Xiaoqi; Eid, Ali H.; Eid, Assaad A.... more authors ... less authors ( Ivyspring International Publisher , 2014 , Article)Both diabetes and cancer are prevalent diseases whose incidence rates are increasing worldwide, especially in countries that are undergoing rapid industrialization changes. Apparently, lifestyle risk factors including diet, ... -
Combination of Angiotensin (1-7) Agonists and Convalescent Plasma as a New Strategy to Overcome Angiotensin Converting Enzyme 2 (ACE2) Inhibition for the Treatment of COVID-19
Issa, Hawraa; Eid, Ali H.; Berry, Bassam; Takhviji, Vahideh; Khosravi, Abbas; Mantash, Sarah; Nehme, Rawan; Hallal, Rawan; Karaki, Hussein; Dhayni, Kawthar; Faour, Wissam H.; Kobeissy, Firas; Nehme, Ali; Zibara, Kazem... more authors ... less authors ( Frontiers , 2021 , Article)Coronavirus disease-2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently the most concerning health problem worldwide. SARS-CoV-2 infects cells by binding to ... -
A comparative study on chemical profiles and biological activities of different extracts of three Verbascum species from Turkey: In vitro, in silico and network pharmacological approaches
Zengin, Gokhan; Yagi, Sakina; Kopjar, Mirela; Ćorković, Ina; Uba, Abdullahi Ibrahim; Yildiztugay, Evren; Kumar, Sathish; Rengasamy, Kannan RR; AlDhaheri, Yusra; Eid, Ali H.... more authors ... less authors ( Elsevier , 2023 , Article)The present study aimed to evaluate the antioxidant and enzyme inhibition properties of aerial part of Verbascum cheiranthifolium Boiss. V. myriocarpum Boiss. & Heldr. and V. pyroliforme (Boiss. & Heldr.) Kuntze as well ... -
Corrigendum to “Peri-renal adipose inflammation contributes to renal dysfunction in a non-obese prediabetic rat model: Role of anti-diabetic drugs” [Biochem. Pharmacol. 186 (2021) 114491]
Hammoud, Safaa H.; AlZaim, Ibrahim; Mougharbil, Nahed; Koubar, Sahar; Eid, Ali H.; Eid, Assaad A.; El-Yazbi, Ahmed F.... more authors ... less authors ( Elsevier , 2023 , Other)We regret to report that a mistake occurred in preparation of Fig. 4. The modified figure is included below. We apologize for any confusion this might have created. -
Could antigen presenting cells represent a protective element during sars-cov-2 infection in children?
Lauro, Rita; Irrera, Natasha; Eid, Ali H.; Bitto, Alessandra ( MDPI , 2021 , Article)Antigen Presenting Cells (APC) are immune cells that recognize, process, and present antigens to lymphocytes. APCs are among the earliest immune responders against an antigen. Thus, in patients with COVID-19, a disease ... -
Covid-19 in pediatric patients: A focus on CHD patients
Zareef, Rana O.; Younis, Nour K.; Bitar, Fadi; Eid, Ali H.; Arabi, Mariam ( Frontiers Media S.A. , 2020 , Article)Coronavirus disease 2019 (COVID-19) is a global pandemic caused by SARS-CoV-2 virus. As of the 30th of September 2020, around 34,000,000 cases have been reported globally. Pediatrics with underlying congenital heart disease ... -
COVID-19: potential therapeutics for pediatric patients
Younis, Nour K.; Zareef, Rana O.; Fakhri, Ghina; Bitar, Fadi; Eid, Ali H.; Arabi, Mariam... more authors ... less authors ( Springer , 2021 , Article Review)The global spread of COVID-19 has imparted significant economic, medical, and social burdens. Like adults, children are affected by this pandemic. However, milder clinical symptoms are often experienced by them. Only a ... -
Cucurbituril Ameliorates Liver Damage Induced by Microcystis aeruginosa in a Mouse Model
Saleh, Na'il; Al-Jassabi, Saad; Eid, Ali H.; Nau, Werner M. ( Frontiers , 2021 , Article)Microcystis aeruginosa is a cyanobacterium that produces a variety of cyclic heptapeptide toxins in freshwater. The protective effects of the macromolecular container cucurbit[7]uril (CB7) were evaluated using mouse models ... -
Cyclic AMP-Rap1A signaling activates RhoA to induce α2c-adrenoceptor translocation to the cell surface of microvascular smooth muscle cells
Jeyaraj, Selvi C.; Unger, Nicholas T.; Eid, Ali H.; Mitra, Srabani; Paul El-Dahdah, N.; Quilliam, Lawrence A.; Flavahan, Nicholas A.; Chotani, Maqsood A.... more authors ... less authors ( American Physiological Society , 2012 , Article)Intracellular signaling by the second messenger cyclic AMP (cAMP) activates the Ras-related small GTPase Rap1 through the guanine exchange factor Epac. This activation leads to effector protein interactions, activation, ... -
Cyclic AMP-Rap1A signaling mediates cell surface translocation of microvascular smooth muscle α2C-adrenoceptors through the actin-binding protein filamin-2
Motawea, Hanaa K. B.; Jeyaraj, Selvi C.; Eid, Ali H.; Mitra, Srabani; Unger, Nicholas T.; Ahmed, Amany A. E.; Flavahan, Nicholas A.; Chotani, Maqsood A.... more authors ... less authors ( American Physiological Society , 2013 , Article)The second messenger cyclic AMP (cAMP) plays a vital role in vascular physiology, including vasodilation of large blood vessels. We recently demonstrated cAMP activation of Epac-Rap1A and RhoA-Rho-associated kinase ... -
Detection of Antinuclear Antibodies Targeting Intracellular Signal Transduction, Metabolism, Apoptotic Processes and Cell Death in Critical COVID-19 Patients
Nasarallah, Gheyath K.; Fakhroo, Aisha D.; Khan, Taushif; Cyprian, Farhan S.; Al Ali, Fatima; Ata, Manar M.A.; Taleb, Sara; Zedan, Hadeel T.; Al-Sadeq, Duaa W.; Amanullah, Fathima H.; Hssain, Ali A.; Eid, Ali H.; Abu-Raddad, Laith J.; Al-Khal, Abdullatif; Al Thani, Asmaa A.; Marr, Nico; Yassine, Hadi M.... more authors ... less authors ( Universita Cattolica del Sacro Cuore , 2022 , Article)Background and Objectives: The heterogeneity of the coronavirus disease of 2019 (COVID-19) lies within its diverse symptoms and severity, ranging from mild to lethal. Acute respiratory distress syndrome (ARDS) is a leading ... -
Determination of vascular reactivity of middle cerebral arteries from stroke and spinal cord injury animal models using pressure myography
Anwar, Mohammad A.; Eid, Ali H. ( Humana Press Inc. , 2016 , Book chapter)Stroke and other neurovascular derangements are main causes of global death. They, along with spinal cord injuries, are responsible for being the principal cause of disability due to neurological and cognitive problems. ... -
Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells via Tryptophan 2,3 Dioxygenase
Cecchi, Marta; Mannini, Antonella; Lapucci, Andrea; Silvano, Angela; Lulli, Matteo; Luceri, Cristina; D’Ambrosio, Mario; Chiarugi, Alberto; Eid, Ali H.; Parenti, Astrid... more authors ... less authors ( Frontiers Media , 2022 , Article)In addition to its well-established immunosuppressive actions, tryptophan 2,3-dioxygenase (TDO) appears to elicit direct effects on tumor cell function. Although TDO has been associated with cancer stemness, its involvement ... -
Diagnostic Value of Non-invasive Liver Function Tests in Liver Fibrosis and Changes in These Parameters Post-metabolic Surgery
Jangjoo, Sara; Emami, Nima; Sahranavard, Mehrdad; Shah, Najeeb Z.; Alidadi, Mona; Baratzadeh, Fatemeh; Sathyapalan, Thozhukat; Eid, Ali H.; Jangjoo, Ali; Jamialahmadi, Tannaz; Sahebkar, Amirhossein... more authors ... less authors ( Springer , 2023 , Article)Purpose: This study aimed to ascertain the diagnostic accuracy of non-invasive liver function tests in liver fibrosis and assess their changes after metabolic surgery. Materials and Methods: 1005 individuals with severe ... -
Drug repurposing in cancer: Now and beyond
Eid, Ali H. (2021 , Other)No Abdtract -
Drug repurposing in neurodegenerative and cardiovascular diseases
Eid, Ali H. ( Bentham Science Publishers , 2021 , Other)No Abstract -
Drug Repurposing in Vasculo-metabolic Diseases
Eid, Ali H. ( Bentham Science Publishers , 2023 , Other)Drug repurposing or repositioning is an approach that seeks to maximize the use of existing drugs by identifying new indications other than the ones for which the drug was initially conceived [1-5]. This approach has been ... -
Dysregulation of angiotensin converting enzyme 2 expression and function in comorbid disease conditions possibly contributes to coronavirus infectious disease 2019 complication severity
Hammoud, Safaa H.; Wehbe, Zena; Abdelhady, Samar; Kobeissy, Firas; Eid, Ali H.; El-Yazbi, Ahmed F.... more authors ... less authors ( American Society for Pharmacology and Experimental Therapy , 2021 , Article Review)ACE2 has emerged as a double agent in the COVID-19 ordeal, as it is both physiologically protective and virally conducive. The identification of ACE2 in as many as 72 tissues suggests that extrapulmonary invasion and damage ...