Browsing by Author "Nasrallah, Gheyath K"
Now showing items 21-40 of 149
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A comprehensive review on the anti-cancer properties and mechanisms of action of sesamin, a lignan in sesame seeds (Sesamum indicum).
Majdalawieh, Amin F.; Massri, Mariam; Nasrallah, Gheyath K. ( Elsevier , 2017 , Article)Sesamin is the major active ingredient is Sesamum indicum seeds. Several studies revealed that sesamin possesses potent anti-cancer properties. The anti-cancer effects of sesamin have been mainly attributed to its ... -
Correction to: Co-prevalence of human Papillomaviruses (HPV) and Epstein–Barr virus (EBV) in healthy blood donors from diverse nationalities in Qatar
Gupta, Ishita; Nasrallah, Gheyath K.; Sharma, Anju; Jabeen, Ayesha; Smatti, Maria K.; Al-Thawadi, Hamda A.; Sultan, Ali A.; Alkhalaf, Moussa; Vranic, Semir; Moustafa, Ala Eddin Al... more authors ... less authors ( BMC , 2020 , Other)Correction to: Cancer Cell Int (2020) 20:107 https://doi.org/10.1186/s12935-020-01190-2 -
Covid-19 Vaccine Protection among Children and Adolescents in Qatar.
Chemaitelly, Hiam; AlMukdad, Sawsan; Ayoub, Houssein H; Altarawneh, Heba N; Coyle, Peter; Tang, Patrick; Yassine, Hadi M; Al-Khatib, Hebah A; Smatti, Maria K; Hasan, Mohammad R; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar H; Latif, Ali N; Shaik, Riyazuddin M; Abdul-Rahim, Hanan F; Nasrallah, Gheyath K; Al-Kuwari, Mohamed G; Al-Romaihi, Hamad E; Butt, Adeel A; Al-Thani, Mohamed H; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J... more authors ... less authors ( Massachusetts Medical Society , 2022 , Article)The BNT162b2 vaccine against coronavirus disease 2019 (Covid-19) has been authorized for use in children 5 to 11 years of age and adolescents 12 to 17 years of age but in different antigen doses. We assessed the real-world ... -
The Current Status of Cytomegalovirus (CMV) Prevalence in the MENA region: a systematic review
Al Mana, Hassan; Yassine, Hadi M.; Youne, Nadin N.; Al-Mohannadi, Anjud; Al-Sadeq, Duaa W.; Alhababi, Dalal; Nasrallah, Gheyath K.... more authors ... less authors ( MDPI , 2019 , Article)Human cytomegalovirus (CMV) is a highly prevalent herpesvirus worldwide. According to the Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO), CMV infects people of all ages, and by ... -
Deletion of potD, encoding a putative spermidine-binding protein, results in a complex phenotype in Legionella pneumophila
Nasrallah, Gheyath K.; Abdelhady, Hany; Tompkins, Nicholas P.; Carson, Kaitlyn R.; Garduno, Rafael A. ( Elsevier GmbH , 2014 , Article)L. pneumophila is an intracellular pathogen that replicates in a membrane-bound compartment known as the Legionella-containing vacuole (LCV). We previously observed that the polyamine spermidine, produced by host cells or ... -
Demographic and Clinical Characteristics of Early Travel-Associated COVID-19 Cases
Marei, Reham M.; Emara, Mohamed M.; Elsaied, Omar M.; Nasrallah, Gheyath K.; Chivese, Tawanda; Al-Romaihi, Hamad E.; Althani, Mohamed H.; Al Thani, Asmaa A.; Farag, Elmoubasher A.; Yassine, Hadi M.... more authors ... less authors ( Frontiers Media , 2020 , Article)© Copyright © 2020 Marei, Emara, Elsaied, Nasrallah, Chivese, Al-Romaihi, Althani, Al Thani, Farag and Yassine. Background: SARS-CoV-2 continues to claim hundreds of thousands of people's lives. It mostly affects the elderly ... -
Demographics and Epidemiology of Hepatitis B in the State of Qatar: A Five-Year Surveillance-Based Incidence Study
Al Romaihi, Hamad E.; Ganesan, Nandakumar; Farag, Elmoubasher A.; Smatti, Maria K.; Nasrallah, Gheyath K.; Himatt, Sayed M.; Derbala, Moutaz F.; Alshamali, Maha; Mahadoon, Lylu K.; Khogali, Hayat S.; Sallam, Mohamed; Al Thani, Asmaa A.; Al Thani, Mohammed; Al Kaabi, Saad; Yassine, Hadi M.... more authors ... less authors ( MDPI , 2019 , Article)Background: Expatriates represent >80% of Qatar’s population, mostly arriving from countries in Africa and Asia that are endemic with many diseases. This increases the risk for introducing new pathogens into the country ... -
Dengue and chikungunya seroprevalence among Qatari nationals and immigrants residing in Qatar.
Humphrey, John M; Al-Absi, Enas S; Hamdan, Munia M; Okasha, Sara S; Al-Trmanini, Diyna M; El-Dous, Hend G; Dargham, Soha R; Schieffelin, John; Abu-Raddad, Laith J; Nasrallah, Gheyath K... more authors ... less authors ( Public Library of Science , 2019 , Article)The objective of this study is to characterize the seroprevalence of anti-dengue (DENV) and anti-chikungunya (CHIKV) antibodies among blood donors residing in Qatar who are Middle East and North Africa (MENA) nationals and ... -
Description of PTPRG genetic variants identified in a cohort of Chronic Myeloid Leukemia patients and their ability to influence response to Tyrosine kinase Inhibitors
Mohamed A., Ismail; Nasrallah, Gheyath K.; Monne, Maria; AlSayab, Ali; Yassin, Mohamed A.; Varadharaj, Govindarajulu; Younes, Salma; Sorio, Claudio; Cook, Richard; Modjtahedi, Helmout; Al-Dewik, Nader I.... more authors ... less authors ( Elsevier , 2022 , Article)Tyrosine kinase inhibitors (TKIs) have remarkably transformed Ph+ chronic myeloid leukemia (CML) management; however, TKI resistance remains a major clinical challenge. Mutations in BCR-ABL1 are well studied but fail to ... -
Detection and Genotyping of Torque Teno Virus (TTV) in Healthy Blood Donors and Patients Infected With HBV or HCV in Qatar
AbuOdeh, Raed; Al-Mawlawi, Naema; Al-Qahtani, Ahmed; Bohol, Marie Fe F.; Al-Ahdal, Mohammed N.; Hasan, Haydar A.; AbuOdeh, Lamees; Nasrallah, Gheyath K.... more authors ... less authors ( Wiley Periodicals, Inc , 2015 , Article)Torque Teno virus (TTV) has been associated with non A–G hepatitis. The goal of this study was to estimate the infection rates and genotypic characteristics of TTV in the State of Qatar. A total of 644 blood samples ... -
Detection and Phylogenetic Analysis of Human Pegivirus (GBV-C) Among Blood Donors and Patients Infected With Hepatitis B Virus (HBV) in Qatar
AbuOdeh, Raed O.; Al-Absi, Enas; Ali, Nadima H.; Khalili, Makiyeh; Al-Mawlawi, Naema; Hadwan, Tameem A.; Al Thani, Asmaa A.; Nasrallah, Gheyath K.... more authors ... less authors ( Wiley , 2015 , Article)Human Pegivirus (HPgV), formerly GB virus-C/ Hepatitis G virus (GBV-C/HGV), collectively known as GBV-C, is widely spread and has been reported to be associated with non-A–E hepatitis. To our knowledge, no previous ... -
Detection of antinuclear antibodies targeting intracellular signal transduction, metabolism, apoptotic processes and cell death in critical COVID-19 patients
Fakhroo, Aisha; Ali, Fatma; Nasrallah, Gheyath K.; Marr, Nico; Yassine, Hadi Mohamad ( Qatar University Press , 2021 , Poster)Background: The heterogeneity of COVID-19 lies within its diverse symptoms and severity, ranging from mild to lethal. Acute respiratory distress syndrome (ARDS) has been shown to be the leading cause of mortality in COVID-19 ... -
Diagnostic Efficiency of Three Fully Automated Serology Assays and Their Correlation with a Novel Surrogate Virus Neutralization Test in Symptomatic and Asymptomatic SARS-COV-2 Individuals
Younes, Salma; Al-Jighefee, Hadeel; Shurrab, Farah; Al-Sadeq, Duaa W.; Younes, Nadin; Dargham, Soha R.; Al-Dewik, Nader; Qotba, Hamda; Syed, Mohamed; Alnuaimi, Ahmed; Yassine, Hadi M.; Tang, Patrick; Abu-Raddad, Laith J.; Nasrallah, Gheyath K.... more authors ... less authors ( MDPI , 2020 , Article)Abstract: To support the deployment of serology assays for population screening during the COVID-19 pandemic, we compared the performance of three fully automated SARS-CoV-2 IgG assays: Mindray CL-900i® (target: spike [S] ... -
Distinct antibody repertoires against endemic human coronaviruses in children and adults.
Khan, Taushif; Rahman, Mahbuba; Al Ali, Fatima; Huang, Susie Sy; Ata, Manar; Zhang, Qian; Bastard, Paul; Liu, Zhiyong; Jouanguy, Emmanuelle; Beziat, Vivien; Cobat, Aurélie; Nasrallah, Gheyath K; Yassine, Hadi M; Smatti, Maria K; Saeed, Amira; Vandernoot, Isabelle; Goffard, Jean-Christophe; Smits, Guillaume; Migeotte, Isabelle; Haerynck, Filomeen; Meyts, Isabelle; Abel, Laurent; Casanova, Jean-Laurent; Hasan, Mohammad R; Marr, Nico... more authors ... less authors ( American Society for Clinical Investigation , 2021 , Article)Four endemic human coronaviruses (HCoVs) are commonly associated with acute respiratory infection in humans. B cell responses to these "common cold" viruses remain incompletely understood. Here we report a comprehensive ... -
Duration of immune protection of SARS-CoV-2 natural infection against reinfection.
Chemaitelly, Hiam; Nagelkerke, Nico; Ayoub, Houssein H; Coyle, Peter; Tang, Patrick; Yassine, Hadi M; Al-Khatib, Hebah A; Smatti, Maria K; Hasan, Mohammad R; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul-Rahim, Hanan F; Nasrallah, Gheyath K; Al-Kuwari, Mohamed Ghaith; Butt, Adeel A; Al-Romaihi, Hamad Eid; Al-Thani, Mohamed H; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J... more authors ... less authors ( Oxford University Press , 2022 , Article)The future of the SARS-CoV-2 pandemic hinges on virus evolution and duration of immune protection of natural infection against reinfection. We investigated duration of protection afforded by natural infection, the effect ... -
Duration of mRNA vaccine protection against SARS-CoV-2 Omicron BA.1 and BA.2 subvariants in Qatar.
Chemaitelly, Hiam; Ayoub, Houssein H; AlMukdad, Sawsan; Coyle, Peter; Tang, Patrick; Yassine, Hadi M; Al-Khatib, Hebah A; Smatti, Maria K; Hasan, Mohammad R; Al-Kanaani, Zaina; Al-Kuwari, Einas; Jeremijenko, Andrew; Kaleeckal, Anvar Hassan; Latif, Ali Nizar; Shaik, Riyazuddin Mohammad; Abdul-Rahim, Hanan F; Nasrallah, Gheyath K; Al-Kuwari, Mohamed Ghaith; Butt, Adeel A; Al-Romaihi, Hamad Eid; Al-Thani, Mohamed H; Al-Khal, Abdullatif; Bertollini, Roberto; Abu-Raddad, Laith J... more authors ... less authors ( Nature Research , 2022 , Article)SARS-CoV-2 Omicron BA.1 and BA.2 subvariants are genetically divergent. We conducted a matched, test-negative, case-control study to estimate duration of protection of the second and third/booster doses of mRNA COVID-19 ... -
Eco-friendly highly efficient BN/rGO/TiO2 nanocomposite visible-light photocatalyst for phenol mineralization
Al-Kandari, Shekhah; Abdullah, Aboubakr M.; Al-Kandari, Halema; Nasrallah, Gheyath K.; Sharaf, Mohammed A.; AlMarzouq, Douaa S.; Mohamed, Ahmed M.; Younes, Nadin; Kafour, Nada; Al-Tahtamouni, Talal... more authors ... less authors ( Springer , 2021 , Article)Boron nitride (BN) and reduced graphene oxide (rGO) of different loadings were composited with commercial P25 TiO2 (Ti) through the hydrothermal method. The as-prepared nanocomposites were characterized using various ... -
Ecotoxicological Assessment of Thermally- and Hydrogen-Reduced Graphene Oxide/TiO₂ Photocatalytic Nanocomposites Using the Zebrafish Embryo Model.
Al-Kandari, Halema; Younes, Nadin; Al-Jamal, Ola; Zakaria, Zain Z; Najjar, Huda; Alserr, Farah; Pintus, Gianfranco; Al-Asmakh, Maha A; Abdullah, Aboubakr M; Nasrallah, Gheyath K... more authors ... less authors ( MDPI , 2019 , Article)Advanced oxidation processes (AOPs) have recently attracted great interest in water pollution management. Using the zebrafish embryo model, we investigated the environmental impacts of two thermally (RGOTi)- and hydrogen ... -
Editorial: Unconventional Animal Models in Infectious Disease Research – Part I
Younes, Nadin; Nasrallah, Gheyath K. ( Frontiers Media , 2021 , Article)Editorial on the Research Topic Unconventional Animal Models in Infectious Disease Research -
Editorial: Unconventional animal models in infectious disease research, volume II
Younes, Salma; Zein, Nouran; Abunasser, Shaden; Kamareddine, Layla; Kirienko, Natalia V.; Nasrallah, Gheyath K.... more authors ... less authors ( Frontiers Media , 2023 , Other)Infectious diseases remain a serious health threat globally, an actuality that necessitates ongoing research in this field. Among different research modalities, the use of animal models to unravel host-pathogen interactions ...