Browsing by Subject "Bias"
Now showing items 1-4 of 4
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Analyzing inherent biases in SARS-CoV-2 PCR and serological epidemiologic metrics
( springer nature , 2022 , Article)Background: Prospective observational data show that infected persons with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain polymerase chain reaction (PCR) positive for a prolonged duration, and that ... -
Biased signaling: A viable strategy to drug ghrelin receptors for the treatment of obesity
( Elsevier , 2021 , Article)Obesity is a global burden and a chronic ailment with damaging overall health effects. Ghrelin, an octanoylated 28 amino acid peptide hormone, is secreted from the oxyntic mucosa of the stomach. Ghrelin acts on regions of ... -
Signaling diversity of mu- and delta- opioid receptor ligands: Re-evaluating the benefits of β-arrestin/G protein signaling bias.
( Elsevier , 2020 , Article)Opioid analgesics are elective for treating moderate to severe pain but their use is restricted by severe side effects. Signaling bias has been proposed as a viable means for improving this situation. To exploit this ... -
The MethodologicAl STandards for Epidemiological Research (MASTER) scale demonstrated a unified framework for bias assessment
( Elsevier Inc. , 2021 , Article)Objective: This paper presents a unified framework for assessment of the methodological quality of analytic study designs. Study Design and Setting: A systematic review of 393 methodological quality assessment tools that ...