Browsing by Subject "GWAS"

Now showing items 1-7 of 7

    • A Whole-Genome Sequencing Association Study of Low Bone Mineral Density Identifies New Susceptibility Loci in the Phase I Qatar Biobank Cohort 

      Younes, Nadin; Abdallah, Atiyeh; Abu madi, Marawan ( Qatar University Press , 2021 , Poster)
      Introduction: Bone density disorders are characterized by a reduction in bone mass density and strength, which lead to an increase in the susceptibility to sudden and unexpected fractures. Despite the serious consequences ...

    • Association of Vitamin D Genetic Risk Score with Noncommunicable Diseases: A Systematic Review 

      Almaghrbi, Heba; Al-Shafai, Mashael; Al-Asmakh, Maha; Bawadi, Hiba ( MDPI , 2023 , Article)
      Background and Aims: The genetic risk score (GRS) is an important tool for estimating the total genetic contribution or susceptibility to a certain outcome of interest in an individual, taking into account their genetic ...

    • Genetic polymorphisms associated with type 2 diabetes in the Arab world: A systematic review and meta-analysis. 

      Abuhendi, Najat; Qush, Abeer; Naji, Fozieh; Abunada, Hanan; Al Buainain, Reeham; ... more authors ( Elsevier , 2019 , Article)
      T2DM reach epidemic levels in the Arab countries. In this study, we aimed to perform a systematic review and meta-analysis to underline the susceptibility genetic profile of Arab patients with T2DM that result from SNPs. ...

    • Genome-wide association study identifies a novel association between a cardiovascular gene polymorphism and superior athletic performance 

      Elrayess, Mohamed; Al-Khelaifi, Fatima; Yousri, Noha; Al-Bagha, Omar ( Qatar University Press , 2020 , Poster)
      Background: Research into the genetic predisposition to superior athletic performance has been a hindered by the underpowered studies and the small effect size of identified genetic variants. The aims of this study were ...

    • Genome-Wide Association Study Reveals a Novel Association Between MYBPC3 Gene Polymorphism, Endurance Athlete Status, Aerobic Capacity and Steroid Metabolism. 

      Al-Khelaifi, Fatima; Yousri, Noha A; Diboun, Ilhame; Semenova, Ekaterina A; Kostryukova, Elena S; ... more authors ( Frontiers Media , 2020 , Article)
      The genetic predisposition to elite athletic performance has been a controversial subject due to the underpowered studies and the small effect size of identified genetic variants. The aims of this study were to investigate ...

    • Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis 

      Kanoni, Stavroula; Graham, Sarah E.; Wang, Yuxuan; Surakka, Ida; Ramdas, Shweta; ... more authors ( BioMed Central , 2022 , Article)
      Background: Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding ...

    • Whole-Genome Sequencing of 100 Genomes Identifies a Distinctive Genetic Susceptibility Profile of Qatari Patients with Hypertension 

      Alsamman, Alsamman M.; Almabrazi, Hakeem; Zayed, Hatem ( MDPI , 2022 , Article)
      Essential hypertension (EH) is a leading risk condition for cardiovascular and renal com-plications. While multiple genes are associated with EH, little is known about its genetic etiology. Therefore, this study aimed to ...