Browsing by Author "Al Moustafa, Ala-Eddin"
Now showing items 1-20 of 45
-
Breast Cancer During Pregnancy: A Marked Propensity to Triple-Negative Phenotype.
( Frontiers Media , 2020 , Article)Breast and cervical cancers comprise 50% of all cancers during pregnancy. In particular, gestational breast cancer is considered one of the most aggressive types of cancers, which is a rare but fatal disease. However, the ... -
Co-Incidence of Epstein-Barr Virus and High-Risk Human Papillomaviruses in Cervical Cancer of Syrian Women.
( Frontiers Media , 2018 , Article)Epstein-Barr virus (EBV) has been recently shown to be co-present with high-risk human papillomaviruses (HPVs) in human cervical cancer; thus, these oncoviruses play an important role in the initiation and/or progression ... -
Co-incidence of Human Papillomaviruses and Epstein-Barr Virus Is Associated With High to Intermediate Tumor Grade in Human Head and Neck Cancer in Syria.
( Frontiers Media , 2020 , Article)High-risk human papillomaviruses (high-risk HPVs) have been recently reported to be co-present with Epstein-Barr virus (EBV) in different types of human cancers including head and neck (HN), where they can cooperate in the ... -
Co-presence of Epstein-Barr virus and high-risk human papillomaviruses in Syrian colorectal cancer samples.
( Taylor & Francis , 2020 , Article)We recently performed two studies exploring the presence of Epstein-Barr virus (EBV) and high-risk human papillomaviruses (HPVs) types 16, 18, 31, 33 and 35 in human colorectal cancers from the Syrian population. Herein, ... -
The co-presence of high-risk human papillomaviruses and Epstein-Barr virus is linked with tumor grade and stage in Qatari women with breast cancer.
( Taylor and Francis , 2020 , Article)High-risk human papillomaviruses (HPV) can be present and cooperate with Epstein-Barr virus (EBV) to promote the onset and/or progression of various cancers including cervical, breast, head and neck as well as colorectal. ... -
Co-presence of human papillomaviruses and Epstein-Barr virus is linked with advanced tumor stage: a tissue microarray study in head and neck cancer patients.
( BMC , 2020 , Article)Human papillomaviruses (HPVs) and Epstein-Barr virus (EBV), known oncoviruses, can be co-present and cooperate in the initiation and/or progression of human carcinomas, including head and neck. Based on this fact, we ... -
Co-prevalence of Epstein-Barr virus and high-risk human papillomaviruses in Syrian women with breast cancer.
( Taylor & Francis , 2016 , Article)ABSTRAT We recently performed 2 studies viewing the presence of Epstein-Barr virus (EBV) and high-risk human papillomaviruses (HPVs) types 16, 18, 31, 33 and 35 in human breast cancer in the Syrian population. Herein, we ... -
Copresence of High-Risk Human Papillomaviruses and Epstein-Barr Virus in Colorectal Cancer: A Tissue Microarray and Molecular Study from Lebanon
( MDPI , 2021 , Article)Colorectal cancer (CRC) is the third most common cause of cancer-related deaths worldwide. Human papillomaviruses (HPVs) and Epstein–Barr virus (EBV) have been reported to be present in different types of human cancers ... -
Crosstalk between HER2 and PD-1/PD-L1 in Breast Cancer: From Clinical Applications to Mathematical Models.
( Springer , 2020 , Article)Breast cancer is one of the major causes of mortality in women worldwide. The most aggressive breast cancer subtypes are human epidermal growth factor receptor-positive (HER2) and triple-negative breast cancers. Therapies ... -
Dasatinib and PD-L1 inhibitors provoke toxicity and inhibit angiogenesis in the embryo
( Elsevier , 2021 , Article)Dasatinib is a targeted cancer therapy, while programmed death ligand 1 (PD-L1) inhibitors are a form of immune checkpoint therapy used to treat various types of cancers. Several studies showed the potential efficacy of ... -
DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL CHALCONE ANALOGS AS POTENTIAL THERAPEUTIC AGENTS FOR CASTRATION RESISTANT PROSTATE CANCER
(2021 , Master Thesis)Prostate cancer (PCa) is the second most frequently diagnosed malignancy, as well as a leading cause of cancer-related mortality in men globally. Despite the initial response to hormonal targeted therapy, the majority of ... -
Design, Synthesis and Biological Evaluation of Novel Chalcone Analogs as Potential Therapeutic Agents for Castration-Resistant Prostate Cancer
( Qatar University Press , 2020 , Poster)Prostate cancer (PCa) is the second most frequently diagnosed malignancy, as well as a leading cause of cancer-related mortality in men globally. Despite the initial response to hormone targeted therapy, the majority of ... -
DNA Damage/Repair Management in Cancers
( MDPI , 2020 , Article Review)DNA damage is well recognized as a critical factor in cancer development and progression. DNA lesions create an abnormal nucleotide or nucleotide fragment, causing a break in one or both chains of the DNA strand. When DNA ... -
E-Cigarette Liquid Provokes Significant Embryotoxicity and Inhibits Angiogenesis.
( MDPI , 2020 , Article)E-cigarette smoking (ECS) is a new method of tobacco smoking that is gaining popularity as it is thought to be a "healthy method" of tobacco consumption. The adverse outcomes of ECS on the respiratory and cardiovascular ... -
E5 and E6/E7 of high-risk HPVs cooperate to enhance cancer progression through EMT initiation
( Taylor & Francis , 2015 , Article)It is estimated that 10–20% of human carcinogenesis is linked to virus infection including papillomaviruses (HPVs). Moreover, since metastatic cancer disease is a major cause of morbidity and mortality in cancer patients, ... -
Editorial: EBV-Associated Carcinomas: Presence, Role, and Prevention Strategies.
( Frontiers Media , 2019 , Other)This special issue addresses an important topic related to the role of Epstein-Barr virus (EBV) in human carcinomas initiation and progression, which is one of the most common viral infections worldwide. Today, the ... -
Epstein-Barr virus (EBV) status in colorectal cancer: a mini review
( Taylor & Francis , 2018 , Article)Epstein-Barr virus (EBV) is a well-characterized oncovirus, associated with several malignancies. The complex and heterogeneous nature of colorectal cancer (CRC) has led to many epidemiological causal associations with ... -
Epstein-Barr Virus and Human Papillomaviruses Interactions and Their Roles in the Initiation of Epithelial-Mesenchymal Transition and Cancer Progression.
( Frontiers Media , 2018 , Article Review)Oncoviruses are implicated in around 20% of all human cancers including both solid and non-solid malignancies. Epstein-Barr virus (EBV) and human papillomaviruses (HPVs) are the most common oncoviruses worldwide. Currently, ... -
Epstein-Barr virus and its association with Fascin expression in colorectal cancers in the Syrian population: A tissue microarray study.
( Taylor & Francis , 2017 , Article)Colorectal cancer (CRC) is the third most common malignancy in both men and women worldwide. Colorectal carcinogenesis is a complex, multistep process involving environmental and lifestyle features as well as sequential ... -
Epstein-Barr Virus in Gliomas: Cause, Association, or Artifact?
( Frontiers Media , 2018 , Article Review)Gliomas are the most common malignant brain tumors and account for around 60% of all primary central nervous system cancers. Glioblastoma multiforme (GBM) is a grade IV glioma associated with a poor outcome despite recent ...
