Title | Author | Publication Date | Publisher | Type |
Analysis of Differentially Expressed Genes and Molecular Pathways in Familial Hypercholesterolemia Involved in Atherosclerosis: A Systematic and Bioinformatics Approach.
| Udhaya Kumar, S; Thirumal Kumar, D; Bithia, R; Sankar, Srivarshini; Magesh, R; Sidenna, Mariem; George Priya Doss, C; Zayed, Hatem... more authors ... less authors | 2020 | Frontiers Media | Article |
A comparative computational approach toward pharmacological chaperones (NN-DNJ and ambroxol) on N370S and L444P mutations causing Gaucher's disease.
| Thirumal Kumar, D; Iyer, Sharada; Christy, J Priyadharshini; Siva, R; Tayubi, Iftikhar Aslam; George Priya Doss, C; Zayed, Hatem... more authors ... less authors | 2019 | Elsevier | Book chapter |
Comprehensive in silico screening and molecular dynamics studies of missense mutations in Sjogren-Larsson syndrome associated with the ALDH3A2 gene.
| Udhaya Kumar, S; Thirumal Kumar, D; Mandal, Pinky D; Sankar, Srivarshini; Haldar, Rishin; Kamaraj, Balu; Walter, Charles Emmanuel Jebaraj; Siva, R; George Priya Doss, C; Zayed, Hatem... more authors ... less authors | 2020 | Elsevier | Article |
Computational and modeling approaches to understand the impact of the Fabry's disease causing mutation (D92Y) on the interaction with pharmacological chaperone 1-deoxygalactonojirimycin (DGJ).
| Thirumal Kumar, D; Judith, E; Priyadharshini Christy, J; Siva, R; Tayubi, Iftikhar Aslam; Chakraborty, Chiranjib; George Priya Doss, C; Zayed, Hatem... more authors ... less authors | 2019 | Elsevier | Book chapter |
A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation causing breast cancer.
| Thirumal Kumar, D; Jain, Nikita; Evangeline, Judith; Kamaraj, Balu; Siva, R; Zayed, Hatem; George Priya Doss, C... more authors ... less authors | 2019 | Elsevier | Article |
Computational approach to unravel the impact of missense mutations of proteins (D2HGDH and IDH2) causing D-2-hydroxyglutaric aciduria 2.
| Thirumal Kumar, D; Jerushah Emerald, L; George Priya Doss, C; Sneha, P; Siva, R; Charles Emmanuel Jebaraj, W; Zayed, Hatem... more authors ... less authors | 2018 | Springer US | Article |
A computational method to characterize the missense mutations in the catalytic domain of GAA protein causing Pompe disease.
| Thirumal Kumar, D; Umer Niazullah, Maryam; Tasneem, Sadia; Judith, E; Susmita, B; George Priya Doss, C; Selvarajan, E; Zayed, Hatem... more authors ... less authors | 2019 | Wiley | Article |
Computational model to analyze and characterize the functional mutations of NOD2 protein causing inflammatory disorder - Blau syndrome.
| Thirumal Kumar, D; Udhaya Kumar, S; Nishaat Laeeque, Ahmed Shaikh; Apurva Abhay, Shivalkar; Bithia, R; Magesh, R; Kumar, Maignana; Zayed, Hatem; George Priya Doss, C... more authors ... less authors | 2020 | Elsevier | Article |
A computational model to predict the structural and functional consequences of missense mutations in O-methylguanine DNA methyltransferase.
| Thirumal Kumar, D; Mendonca, Enid; Priyadharshini Christy, J; George Priya Doss, C; Zayed, Hatem | 2019 | Elsevier | Article |
Computational modelling approaches as a potential platform to understand the molecular genetics association between Parkinson's and Gaucher diseases.
| Thirumal Kumar, D; Eldous, Hend Ghasan; Mahgoub, Zainab Alaa; George Priya Doss, C; Zayed, Hatem | 2018 | Springer | Article |
Dysregulation of Signaling Pathways Due to Differentially Expressed Genes From the B-Cell Transcriptomes of Systemic Lupus Erythematosus Patients - A Bioinformatics Approach.
| Udhaya Kumar, S; Thirumal Kumar, D; Siva, R; George Priya Doss, C; Younes, Salma; Younes, Nadin; Sidenna, Mariem; Zayed, Hatem... more authors ... less authors | 2020 | Frontiers Media | Article |
Elucidating the role of interacting residues of the MSH2-MSH6 complex in DNA repair mechanism: A computational approach.
| Thirumal Kumar, D; Susmita, B; Judith, E; Priyadharshini Christy, J; George Priya Doss, C; Zayed, Hatem... more authors ... less authors | 2019 | Elsevier | Article |
Identification of potential inhibitors against pathogenic missense mutations of PMM2 using a structure-based virtual screening approach.
| Thirumal Kumar, D; Jain, Nikita; S, Udhaya Kumar; GeorgePriya Doss, C; Zayed, Hatem | 2019 | Taylor & Francis | Article |
Impact of missense mutations in survival motor neuron protein (SMN1) leading to Spinal Muscular Atrophy (SMA): A computational approach.
| Sneha, P; Zenith, Tanzila U; Abu Habib, Ummay Salma; Evangeline, Judith; Thirumal Kumar, D; George Priya Doss, C; Siva, R; Zayed, Hatem... more authors ... less authors | 2018 | Springer US | Article |
Investigating the structural impacts of a novel missense variant identified with whole exome sequencing in an Egyptian patient with propionic acidemia
| Ibrahim, Ali Zaki; Thirumal Kumar, D; Abunada, Taghreed; Younes, Salma; George Priya Doss, C; Zaki, Osama K; Zayed, Hatem... more authors ... less authors | 2020 | Elsevier | Article |
Molecular dynamics simulations to decipher the structural and functional consequences of pathogenic missense mutations in the galactosylceramidase (GALC) protein causing Krabbe's disease.
| Thirumal Kumar, D; Jain, Nikita; Udhaya Kumar, S; Jena, Prangya Paramita; Ramamoorthy, Siva; George Priya Doss, C; Zayed, Hatem... more authors ... less authors | 2020 | Taylor & Francis | Article |