Title | Author | Publication Date | Publisher | Type |
A comparative computational approach toward pharmacological chaperones (NN-DNJ and ambroxol) on N370S and L444P mutations causing Gaucher's disease.
| Thirumal Kumar, D; Iyer, Sharada; Christy, J Priyadharshini; Siva, R; Tayubi, Iftikhar Aslam; George Priya Doss, C; Zayed, Hatem | 2019 | Elsevier | Book chapter |
Computational and modeling approaches to understand the impact of the Fabry's disease causing mutation (D92Y) on the interaction with pharmacological chaperone 1-deoxygalactonojirimycin (DGJ).
| Thirumal Kumar, D; Judith, E; Priyadharshini Christy, J; Siva, R; Tayubi, Iftikhar Aslam; Chakraborty, Chiranjib; George Priya Doss, C; Zayed, Hatem | 2019 | Elsevier | Book chapter |
A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation causing breast cancer.
| Thirumal Kumar, D; Jain, Nikita; Evangeline, Judith; Kamaraj, Balu; Siva, R; Zayed, Hatem; George Priya Doss, C | 2019 | Elsevier | Article |
Computational approach to unravel the impact of missense mutations of proteins (D2HGDH and IDH2) causing D-2-hydroxyglutaric aciduria 2.
| Thirumal Kumar, D; Jerushah Emerald, L; George Priya Doss, C; Sneha, P; Siva, R; Charles Emmanuel Jebaraj, W; Zayed, Hatem | 2018 | Springer US | Article |
A computational method to characterize the missense mutations in the catalytic domain of GAA protein causing Pompe disease.
| Thirumal Kumar, D; Umer Niazullah, Maryam; Tasneem, Sadia; Judith, E; Susmita, B; George Priya Doss, C; Selvarajan, E; Zayed, Hatem | 2019 | Wiley | Article |
A computational model to predict the structural and functional consequences of missense mutations in O-methylguanine DNA methyltransferase.
| Thirumal Kumar, D; Mendonca, Enid; Priyadharshini Christy, J; George Priya Doss, C; Zayed, Hatem | 2019 | Elsevier | Article |
Computational modelling approaches as a potential platform to understand the molecular genetics association between Parkinson's and Gaucher diseases.
| Thirumal Kumar, D; Eldous, Hend Ghasan; Mahgoub, Zainab Alaa; George Priya Doss, C; Zayed, Hatem | 2018 | Springer | Article |
Elucidating the role of interacting residues of the MSH2-MSH6 complex in DNA repair mechanism: A computational approach.
| Thirumal Kumar, D; Susmita, B; Judith, E; Priyadharshini Christy, J; George Priya Doss, C; Zayed, Hatem | 2019 | Elsevier | Article |
Impact of missense mutations in survival motor neuron protein (SMN1) leading to Spinal Muscular Atrophy (SMA): A computational approach.
| Sneha, P; Zenith, Tanzila U; Abu Habib, Ummay Salma; Evangeline, Judith; Thirumal Kumar, D; George Priya Doss, C; Siva, R; Zayed, Hatem | 2018 | Springer US | Article |