Browsing by Author "Thirumal Kumar, D"

Now showing items 1-16 of 16

    TitleAuthorPublication DatePublisherType
    Analysis of Differentially Expressed Genes and Molecular Pathways in Familial Hypercholesterolemia Involved in Atherosclerosis: A Systematic and Bioinformatics Approach.  Udhaya Kumar, S; Thirumal Kumar, D; Bithia, R; Sankar, Srivarshini; Magesh, R; ... more authors 2020Frontiers MediaArticle
    A comparative computational approach toward pharmacological chaperones (NN-DNJ and ambroxol) on N370S and L444P mutations causing Gaucher's disease.  Thirumal Kumar, D; Iyer, Sharada; Christy, J Priyadharshini; Siva, R; Tayubi, Iftikhar Aslam; ... more authors 2019ElsevierBook chapter
    Comprehensive in silico screening and molecular dynamics studies of missense mutations in Sjogren-Larsson syndrome associated with the ALDH3A2 gene.  Udhaya Kumar, S; Thirumal Kumar, D; Mandal, Pinky D; Sankar, Srivarshini; Haldar, Rishin; ... more authors 2020ElsevierArticle
    Computational and modeling approaches to understand the impact of the Fabry's disease causing mutation (D92Y) on the interaction with pharmacological chaperone 1-deoxygalactonojirimycin (DGJ).  Thirumal Kumar, D; Judith, E; Priyadharshini Christy, J; Siva, R; Tayubi, Iftikhar Aslam; ... more authors 2019ElsevierBook chapter
    A computational approach for investigating the mutational landscape of RAC-alpha serine/threonine-protein kinase (AKT1) and screening inhibitors against the oncogenic E17K mutation causing breast cancer.  Thirumal Kumar, D; Jain, Nikita; Evangeline, Judith; Kamaraj, Balu; Siva, R; ... more authors 2019ElsevierArticle
    Computational approach to unravel the impact of missense mutations of proteins (D2HGDH and IDH2) causing D-2-hydroxyglutaric aciduria 2.  Thirumal Kumar, D; Jerushah Emerald, L; George Priya Doss, C; Sneha, P; Siva, R; ... more authors 2018Springer USArticle
    A computational method to characterize the missense mutations in the catalytic domain of GAA protein causing Pompe disease.  Thirumal Kumar, D; Umer Niazullah, Maryam; Tasneem, Sadia; Judith, E; Susmita, B; ... more authors 2019WileyArticle
    Computational model to analyze and characterize the functional mutations of NOD2 protein causing inflammatory disorder - Blau syndrome.  Thirumal Kumar, D; Udhaya Kumar, S; Nishaat Laeeque, Ahmed Shaikh; Apurva Abhay, Shivalkar; Bithia, R; ... more authors 2020ElsevierArticle
    A computational model to predict the structural and functional consequences of missense mutations in O-methylguanine DNA methyltransferase.  Thirumal Kumar, D; Mendonca, Enid; Priyadharshini Christy, J; George Priya Doss, C; Zayed, Hatem2019ElsevierArticle
    Computational modelling approaches as a potential platform to understand the molecular genetics association between Parkinson's and Gaucher diseases.  Thirumal Kumar, D; Eldous, Hend Ghasan; Mahgoub, Zainab Alaa; George Priya Doss, C; Zayed, Hatem2018SpringerArticle
    Dysregulation of Signaling Pathways Due to Differentially Expressed Genes From the B-Cell Transcriptomes of Systemic Lupus Erythematosus Patients - A Bioinformatics Approach.  Udhaya Kumar, S; Thirumal Kumar, D; Siva, R; George Priya Doss, C; Younes, Salma; ... more authors 2020Frontiers MediaArticle
    Elucidating the role of interacting residues of the MSH2-MSH6 complex in DNA repair mechanism: A computational approach.  Thirumal Kumar, D; Susmita, B; Judith, E; Priyadharshini Christy, J; George Priya Doss, C; ... more authors 2019ElsevierArticle
    Identification of potential inhibitors against pathogenic missense mutations of PMM2 using a structure-based virtual screening approach.  Thirumal Kumar, D; Jain, Nikita; S, Udhaya Kumar; GeorgePriya Doss, C; Zayed, Hatem2019Taylor & FrancisArticle
    Impact of missense mutations in survival motor neuron protein (SMN1) leading to Spinal Muscular Atrophy (SMA): A computational approach.  Sneha, P; Zenith, Tanzila U; Abu Habib, Ummay Salma; Evangeline, Judith; Thirumal Kumar, D; ... more authors 2018Springer USArticle
    Investigating the structural impacts of a novel missense variant identified with whole exome sequencing in an Egyptian patient with propionic acidemia  Ibrahim, Ali Zaki; Thirumal Kumar, D; Abunada, Taghreed; Younes, Salma; George Priya Doss, C; ... more authors 2020ElsevierArticle
    Molecular dynamics simulations to decipher the structural and functional consequences of pathogenic missense mutations in the galactosylceramidase (GALC) protein causing Krabbe's disease.  Thirumal Kumar, D; Jain, Nikita; Udhaya Kumar, S; Jena, Prangya Paramita; Ramamoorthy, Siva; ... more authors 2020Taylor & FrancisArticle