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المؤلفGanji, Vijay
المؤلفTangpricha, Vin
المؤلفXu, Zhang
تاريخ الإتاحة2020-03-11T05:37:31Z
تاريخ النشر2020-03-10
اسم المنشورNutrients
المعرّفhttp://dx.doi.org/10.3390/nu12030730
الاقتباسGanji, V.; Tangpricha, V.; Zhang, X. Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitness in US Adults. Nutrients 2020, 12, 730.
معرّف المصادر الموحدhttp://hdl.handle.net/10576/13278
الملخصA serum vitamin D [25-hydroxyvitamin D, 25(OH)D] concentration of ≥75 nmol/L is recommended for optimal health. We investigated the relationship between serum 25(OH)D and metabolic syndrome (MetS), diabetes, cardiometabolic biomarkers, and cardiorespiratory fitness (CRF) in US adults using clinical cut points recommended by health organizations. Data from the USA’s National Health and Nutrition Examination Surveys were used. Prevalences and the likelihood of having MetS and diabetes according to clinical cut-points for serum 25(OH)D (<30 nmol/L, 30-<50 nmol/L, 50-<75 nmol/L, and ≥75 nmol/L) were determined with multivariate logistic regression. Relations between serum 25(OH)D and various cardiometabolic biomarkers, CRF, MetS, and diabetes were tested using multivariable-adjusted regression. Prevalence of MetS and diabetes were significantly lower in individuals with serum 25(OH)D ≥75 nmol/L (MetS, 21.6%; diabetes, 4.1%) compared to those with 25(OH)D <30 nmol/L (MetS, 45.5%; diabetes, 11.6%) (p < 0.0001). Individuals with serum 25(OH)D ≥75 nmol/L had significantly lower waist circumference (p < 0.0001), C-reactive protein (p = 0.003), glycated hemoglobin (p < 0.0002), fasting triglycerides (p < 0.0001), total homocysteine (p < 0.0001), and insulin resistance (p = 0.0001) and had significantly higher HDL-cholesterol (p < 0.0001) and maximal oxygen uptake (marker for CRF) (p< 0.0009) compared to those with 25(OH)D <30 nmol/L. In conclusion, serum 25(OH)D ≥75 nmol/L is associated with positive indicators related to cardiometabolic diseases in US adults.
راعي المشروعThe publication of this article was funded by the Qatar National Library
اللغةen
الناشرMDPI
الموضوعcardiometabolic diseases
cardiorespiratory fitness
diabetes
metabolic syndrome
National Health and Nutrition Examination Surveys
USA
vitamin D
العنوانSerum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitness in US Adults
النوعArticle
رقم العدد3
رقم المجلد12
ESSN2072-6643
dc.accessType Open Access


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