Reproducibility of measurement techniques used for creatine kinase, interleukin-6 and high-sensitivity C-reactive protein determination over a 48 h period in males and females
المؤلف | Chrismas B. |
المؤلف | Taylor L. |
المؤلف | Smith A. |
المؤلف | Pemberton P. |
المؤلف | Siegler J.C. |
المؤلف | Midgley A.W. |
تاريخ الإتاحة | 2020-03-18T08:10:11Z |
تاريخ النشر | 2018 |
اسم المنشور | Measurement in Physical Education and Exercise Science |
المصدر | Scopus |
الرقم المعياري الدولي للكتاب | 1091367X |
الملخص | To examine the reproducibility of three measurement techniques used to determine creatine kinase, interleukin-6 and high-sensitivity C-reactive protein, 50 participants had blood samples taken on two occasions. Fingertip plasma samples were analysed using the Reflotron for CK determination. Venous blood samples collected into serum separator tubes were used for IL-6 and hs-CRP analyses. IL-6 was measured using an enzyme linked immune assay development kit. The hs-CRP was measured by an in-house ELISA method. Dependent t-tests showed no systematic bias between samples. The interdian CV was 20.0% for CK, 15.3% for IL-6 and 44.2% for hs-CRP. The intraclass correlation coefficient was 0.90 for CK, 0.98 for IL-6 and 0.70 for hs-CRP. The 95% limits of agreement were ?69.7 to 63.5 IU/L for CK, ?1.48 to 1.80?pg/ml for IL-6 and ?1.10 to 0.91??g/L for hs-CRP. The results demonstrate low absolute reproducibility, which may obscure a true experimental effect. ? 2018, ? 2018 Taylor & Francis. |
راعي المشروع | Association of Anaesthetists of Great Britain and Ireland, University of Western Sydney, Aspetar Orthopaedic and Sports Medicine Hospital, Central Manchester University Hospitals NHS Foundation Trust, Loughborough University, College of Arts and Sciences, Boston University, University of Hull |
اللغة | en |
الناشر | Routledge |
الموضوع | biomarkers cytokines Exercise induced muscle damage inflammation reliability |
النوع | Article |
الصفحات | 191 - 199 |
رقم العدد | 3 |
رقم المجلد | 22 |
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