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Prevalence of antinuclear antibodies (ANA) among healthy individuals with different nationalities in Qatar
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Qatar University Press
, 2020 , Poster)
ANA can be often found in healthy individuals and in many autoimmune diseases. However, its prevalence in healthy individuals is not well investigated in Asia and MENA region. Therefore, aim of this study was to estimate ...
An online module to evaluate the validity of an algorithm to assess the risk for drug-induced QTc prolongation in the psychiatric population
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Qatar University Press
, 2020 , Poster)
Introduction: QTc interval prolongation leads to serious complications making it a concern for all clinicians. Assessing the risk of QTc interval prolongation, especially in the psychiatric population, can be challenging ...
An Investigation into the Prevalence of Behavioral and Environmental determinants of cataract
(
Qatar University Press
, 2020 , Poster)
Accounting for 51% of legal blindness in the world and 27% in Qatar,cataract remains the most prevelant cause of visual imapairments. Cataract involves the clouding of the eye lens, which reduces the light that reaches the ...
Induction of Glyoxalase 1 to prevent Methylglyoxal-Induced Insulin Resistance in Cardiomyocytes
(
Qatar University Press
, 2020 , Poster)
Background: Type 2 Diabetes mellitus is characterized by hyperglycemia and insulin resistance. Methylglyoxal (MG) a highly reactive dicarbonyl compound is also increased in diabetes. MG is detoxified by glyoxalase 1 (Glo-1) ...
Investigating the cardiac effects of Sildenafil loaded nanoparticles on heart failure using the Zebrafish Embryo Model.
(
Qatar University Press
, 2020 , Poster)
Background: Cardiovascular diseases (CVDs) are the first cause of death worldwide. Vasolidator agents are used to relax cardiac muscle, but their extremely short half-lifes limit their effectiveness. Sildenafil is such an ...
Investigating the Cardiac Effects of New Generation Anti-Diabetic Drug EmpagliflozinUsing Zebrafish Embryo Model
(
Qatar University Press
, 2020 , Poster)
Type 2 diabetes mellitus (T2DM) affects >16% of adults in Qatar. Newly emerging class of anti-diabetic drugs focuses on SGLT inhibition were observed to reduce CVDs risks in diabetic patients. Up to date, the mechanism ...
Toxicity Evaluation of Stearamidopropyl Dimethylamine Surfactant on Embryonic Development of Zebrafish
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Qatar University Press
, 2020 , Poster)
Background: Surfactants best known for their use in the industry of detergents, household products, and cosmetics. Usually, the amount of released surfactants into the environment is diluted during secondary water treatment. ...
Hepatic Gene Expression Profile of Lipid Metabolism of Obese Mice After Treatment with AntiObesity Drug
(
Qatar University Press
, 2020 , Poster)
Obesity is a global disorder with multifactorial causes. The liver plays a vital role in fat metabolism. Disorder of hepatic fat metabolism is associated with obesity and causes fatty liver. High fat diet intake (HFD) to ...
Glucose and transferrin liganded PLGA nanoparticles internalization in non-small cell lung cancer cells
(
Qatar University Press
, 2020 , Poster)
Introduction: Recently, after a decade of confusing results, several studies pointed out that overexpression of GLUT1 (glucose transporter 1) is a biomarker of worse prognosis in NSCLC. Nonetheless, the presence of Transferrin ...
Effect of hyperglycemia on EPCs function and regenerative ability
(
Qatar University Press
, 2020 , Poster)
Diabetes induced hyperglycemia increases the risk of cardiovascular complications as it impacts vascular endothelial cells causing vascular dysfunction. Endothelial progenitor cells (EPCs) have been suggested to participate ...