تصفح Theme 5: Covid-19 Research حسب المؤلف "Yassine, Hadi M."
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Evaluation of reverse transcription-loop-mediated isothermal amplification (RT-LAMP) for detecting SARS-CoV-2 in clinical, environmental and animal samples.
Benslimane, Fatiha M.; Al-Jamal, Ola; Boughattas, Sonia|Al Thani, Asmaa A; Yassine, Hadi M. ( Qatar University Press , 2020 , Poster)Background: First described 20 years ago by Notomi et al., the loop-mediated isothermal amplification (LAMP) assay is robust, rapid and straightforward, yet retains high sensitivity and specificity. These features have ... -
Host genetic variants potentially associated with SARS-CoV-2: A multi-population analysis
Smatti, Maria K.; Al-Sarraj, Yasser; Albagha, Omar; Yassine, Hadi M. ( Qatar University Press , 2020 , Poster)Background: Clinical outcomes of coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) showed enormous inter-individual and inter-population differences, possibly ... -
Nanopore Sequencing SARS-CoV-2 genome in Qatar
Benslimane, Fatiha M.; Al Khatib, Hebah; Albatesh, Dana; Al-Jamal, Ola; Boughattas, Sonia; Althani, Asmaa A.; Yassine, Hadi M.... more authors ... less authors ( Qatar University Press , 2020 , Poster)Background: The current pandemic, COVID-19, is cause by an RNA coronavirus that was recently identified as SARS-CoV-2. RNA viruses tend to have a high mutation rate; the rate is around a million times greater than that of ... -
Virtual screening of anti-viral drugs and natural compounds for potential inhibition of the novel SARS-CoV-2 spike receptor-binding domain
Mathew, Shilu M.; Benslimane, Fatiha; Althani, Asmaa A.; Yassine, Hadi M. ( Qatar University Press , 2020 , Poster)Background: The spike (S) protein of SARS-CoV-2 harbors the receptor-binding domain (RBD) that mediates the virus's entry to host cells. The aim of this study was to identify novel inhibitors that target the RBD domain of ... -
Within-host diversity of SARS-CoV-2 in COVID-19 patients with variable disease severities
Al Khatib, Hebah A.; Benslimane, Fatiha M.; El Bashir, Israa; Al Thani, Asmaa A; Yassine, Hadi M. ( Qatar University Press , 2020 , Poster)Background: The ongoing pandemic of SARS-COV-2 has already infected more than eight million people worldwide. The majority of COVID-19 patients are either asymptomatic or have mild symptoms. Yet, about 15% of the cases ...