• English
    • العربية
  • العربية 
  • Login
  • QU
  • QU Library
  •  Home
  • Communities & Collections
  • Help
    • Item Submission
    • Publisher policies
    • User guides
    • FAQs
  • About QSpace
    • Vision & Mission
    • QSpace policies
Advanced Search
Advanced Search
View Item 
  •   Qatar University QSpace
  • Academic
  • University Publications
  • QU Forum Proceedings
  • Qatar University Annual Research Forum & Exhibition
  • QUARFE 2020
  • Theme 2: Population, Health & Wellness
  • View Item
  • Qatar University QSpace
  • Academic
  • University Publications
  • QU Forum Proceedings
  • Qatar University Annual Research Forum & Exhibition
  • QUARFE 2020
  • Theme 2: Population, Health & Wellness
  • View Item
  •      
  •  
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Between Immunity, Metabolism, and Development: A story of a Fly Gut!

    Icon
    View/Open
    Between Immunity, Metabolism, and Development A story of a Fly Gut!.pdf (1.554Mb)
    Date
    2020
    Author
    Kamareddine, Layla
    Najjar, Hoda
    Mohbeddin, Abeer
    Haj Ahmed, Nawar
    Watnick, Paula
    Metadata
    Show full item record
    Abstract
    In addition to its role in initiating immune response in the body, the innate immune system seems to also play a critical role in maintaining homeostatic balance in the gut epithelium. Our recent studies in the Drosophila melanogaster fruit fly model suggest that different innate immune pathways contribute to this homeostatic balance through activating the transcription of genes encoding antimicrobial peptides. We provide evidence that several metabolic parameters are altered in immune deficient flies. We also highlight a role of the gut flora, particularly through its short chain fatty acid, in contributing to this metabolic balance. Interestingly, our data suggest that impaired immunity and metabolic alteration, in turn, exhibit an effect on host development. Collectively, these findings provide evidence that innate immune pathways not only provide the first line of defense against infection but also contribute to host metabolism and development
    URI
    https://doi.org/10.29117/quarfe.2020.0141
    DOI/handle
    http://hdl.handle.net/10576/16724
    Collections
    • Theme 2: Population, Health & Wellness [‎118 ‎ items ]

    entitlement


    QSpace is a digital collection operated and maintained by the Qatar University Library and supported by the ITS department

    Contact Us | Send Feedback
    Contact Us | Send Feedback | QU

     

     

    Home

    Submit your QU affiliated work

    Browse

    All of QSpace
      Communities & Collections Publication Date Author Title Subject Type Language
    This Collection
      Publication Date Author Title Subject Type Language

    My Account

    Login

    Statistics

    View Usage Statistics

    About QSpace

    Vision & Mission QSpace policies

    Help

    Item Submission Publisher policiesUser guides FAQs

    QSpace is a digital collection operated and maintained by the Qatar University Library and supported by the ITS department

    Contact Us | Send Feedback
    Contact Us | Send Feedback | QU

     

     

    Video