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    Rapid diagnostics of coronavirus disease 2019 in early stages using nanobiosensors: Challenges and opportunities

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    Date
    2021-02-01
    Author
    Sharifi, Majid
    Hasan, Anwarul
    Haghighat, Setareh
    Taghizadeh, Akbar
    Attar, Farnoosh
    Bloukh, Samir Haj
    Edis, Zehra
    Xue, Mengzhou
    Khan, Suliman
    Falahati, Mojtaba
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    Abstract
    The rapid outbreak of coronavirus disease 2019 (COVID-19) around the world is a tragic and shocking event that demonstrates the unpreparedness of humans to develop quick diagnostic platforms for novel infectious diseases. In fact, statistical reports of diagnostic tools show that their accuracy, specificity and sensitivity in the detection of COVID hampered by some challenges that can be eliminated by using nanoparticles (NPs). In this study, we aimed to present an overview on the most important ways to diagnose different kinds of viruses followed by the introduction of nanobiosensors. Afterward, some methods of COVID-19 detection such as imaging, laboratory and kit-based diagnostic tests are surveyed. Furthermore, nucleic acids/protein- and immunoglobulin (Ig)-based nanobiosensors for the COVID-19 detection infection are reviewed. Finally, current challenges and future perspective for the development of diagnostic or monitoring technologies in the control of COVID-19 are discussed to persuade the scientists in advancing their technologies beyond imagination. In conclusion, it can be deduced that as rapid COVID-19 detection infection can play a vital role in disease control and treatment, this review may be of great help for controlling the COVID-19 outbreak by providing some necessary information for the development of portable, accurate, selectable and simple nanobiosensors.
    URI
    https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85092068394&origin=inward
    DOI/handle
    http://dx.doi.org/10.1016/j.talanta.2020.121704
    http://hdl.handle.net/10576/16820
    Collections
    • COVID-19 Research [‎849‎ items ]
    • Mechanical & Industrial Engineering [‎1496‎ items ]

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