Qatar University Institutional Repository: المرسلات الحديثة
السجلات المعروضة 981 -- 1000 من 31561
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Regioselective domino C–C/C–O arylation of 1,2,3-triiodobenzenes and 1,3-diketones: Synthesis and in silico evaluation of 7-iodobenzo[b]furan as potential ALK inhibitors
( Elsevier , 2025 , Article)We report a simple, direct, and regioselective protocol for the synthesis of 2,3-disubstituted 7-iodobenzo[b]furans via domino double CC/CO arylations of 1,2,3-triiodobenzene and 1,3-dicarbonyl compounds. Remarkably, the ... -
Highly fluorescent push-pull bis-coumarinyl sulfone: Synthesis, photophysical behavior, and solvatochromic response
( Elsevier , 2025 , Article)In this work, 3,3′-sulfonylbis(7-(diethylamino)-2H-chromen-2-one), an effective fluorescent push-pull system, is synthesized and photophysically characterized. The donor-π–acceptor–π–donor (D–π–A–π–D) architecture of the ... -
Global trends in preclinical and clinical undergraduate endodontic education: A worldwide survey
( nature , 2025 , Article)This is a global study that evaluated the undergraduate endodontic curriculum in dental schools worldwide. An online questionnaire sent to faculty members involved in undergraduate endodontic teaching at 50 dental institutions ... -
The effect of clear aligner and fixed orthodontic treatment on the development of pulp stones: a retrospective observational study.
( EH Angle Education and Research Foundation Inc , 2025 , Article)To report the prevalence of pulp stones (PSs) in molars of orthodontically treated patients, investigate the impact of orthodontic treatment (ORT) using clear aligners (CAs) and fixed appliances (FAs) on the development ... -
Preparedness of Dental Undergraduates for Clinical Practice: A Comparison Between Evaluations by Students and Academic Faculty
( Wiley , 2025 , Article)Introduction: Undergraduate dental education aims to equip students with scientific knowledge, clinical skills, and behavioral attributes to prepare them for a career in independent dental practice after graduation. The ... -
Pain control following impacted mandibular third molar surgery: a comparison of the effectiveness of two different protocols.
( nature , 2025 , Article)The use of multimodal analgesia is a common practice in clinical settings, where a combination of drugs with different mechanisms of action is used to enhance the effectiveness of an analgesic and reduce its adverse effects. ... -
Pharmacological strategies to bridge the gap between cancer and cardiovascular therapeutics
( Elsevier , 2025 , Article)Throughout the history of biomedical research, few endeavors have proven as formidable as the quest to defeat or overcome cancer and cardiovascular diseases (CVDs). Indeed, these twin scourges continue to distress humanity ... -
From bone sentinel to immune savant: Vitamin D and its receptor’s pharmacology
( Elsevier , 2025 , Article)The journey of vitamin D from a simple bone health nutrient to a complex immunomodulator is a testament to the evolving and dynamic nature of scientific understanding. Reflecting on the centennial of vitamin D’s discovery, ... -
Pharmacotherapeutic opportunities within the Hippo signaling pathway
( Elsevier , 2025 , Article)The Hippo pathway is a master of cellular regulation. It modulates intricate mechanisms that govern organ size, tissue homeostasis, and regeneration. Guo et al (2025) dissect the pathway’s multifaceted nature. Their article ... -
Reversing the odds: Advanced and emerging therapeutic strategies for male infertility
( Elsevier , 2025 , Article)Male infertility is a complex and multifaceted condition that has substantial consequences, highlighting the importance and necessity of viable sperm for conception. Despite all the advances in assisted reproductive ... -
Drugging dancing protein clouds: A close look at disorder-based drug design
( Elsevier , 2025 , Article)Since it was established in the late 19th century, the traditional “lock-and-key” model of protein functionality has been foundational in biochemistry, particularly with respect to protein structure and function (Fischer, ... -
Evaluating artificial intelligence chatbots for patient education in oral and maxillofacial radiology
( Elsevier , 2025 , Article)ObjectiveThis study aimed to compare the quality and readability of the responses generated by 3 publicly available artificial intelligence (AI) chatbots in answering frequently asked questions (FAQs) related to Oral and ... -
Beyond the stomach stall: Current and emerging pharmacotherapeutics for gastroparesis
( Elsevier , 2025 , Article)Gastroparesis is a gastrointestinal motility disorder characterized by delayed gastric emptying, which precipitates symptoms like nausea, vomiting, early satiety, and bloating. Diagnosis requires evidence of delayed gastric ... -
Quantitative prediction of toxicological points of departure using two-stage machine learning models: A new approach methodology (NAM) for chemical risk assessment
( Elsevier , 2025 , Article)Point of departure (POD) is a concept used in risk assessment to calculate the reference dose of exposure that is likely to have no appreciable risk on health. POD can be directly utilized from no observed adverse effect ... -
Young bone marrow transplantation delays bone aging in old mice
( Elsevier , 2025 , Article)Recent discoveries have shown that systemic manipulations, such as parabiosis, blood exchange, and young plasma transfer, can counteract many hallmarks of aging. This rejuvenation effect has been attributed to circulatory ... -
Hepatitis C virus transmission among people who inject drugs in the Middle East and North Africa: mathematical modeling analyses of incidence and intervention impact
( Elsevier , 2025 , Article)BackgroundThe Middle East and North Africa (MENA) region is the most affected by hepatitis C virus (HCV) infection globally. This study aimed to estimate HCV incidence among people who inject drugs (PWID) in MENA and ... -
New world of big data—new challenges for evidence synthesis: impact of data duplication on estimates generated by meta-analyses and the development of a framework for its identification and management
( Elsevier , 2024 , Article)ObjectivesThe aim of this study was to highlight the effects of entering duplicated or overlapping data from published studies using the same data registries into a meta-analysis, including its identification and management ... -
Regional variations in incidence of surgical site infection and associated risk factors in women undergoing cesarean section: A systematic review and Meta-Analysis
( Elsevier , 2025 , Article)BackgroundSurgical site infections (SSIs) are the most common postoperative complications after cesarean section (CS), with increased mortality, prolonged hospital stays, and increased healthcare costs. ObjectiveTo ... -
Oral Cancer Knowledge and Screening Practices Among Dental Professionals in Yemen: a Web-Based Survey
( Elsevier , 2025 , Article)BackgroundGood knowledge and screening practices of dental professionals for oral cancer (OC) will inevitably improve its prognosis. The present study sought to evaluate OC knowledge and practices among dental professionals ... -
Machine learning for predicting outcomes of transcatheter aortic valve implantation: A systematic review
( Elsevier , 2025 , Article)BackgroundTranscatheter aortic valve implantation (TAVI) therapy has demonstrated its clear benefits such as low invasiveness, to treat aortic stenosis. Despite associated benefits, still post-procedural complications might ...
