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المؤلفAlshehri, Reem
المؤلفIlyas, Asad Muhammad
المؤلفHasan, Anwarul
المؤلفArnaout, Adnan
المؤلفAhmed, Farid
المؤلفMemic, Adnan
تاريخ الإتاحة2021-07-05T10:58:31Z
تاريخ النشر2016
اسم المنشورJournal of Medicinal Chemistry
المصدرScopus
معرّف المصادر الموحدhttp://dx.doi.org/10.1021/acs.jmedchem.5b01770
معرّف المصادر الموحدhttp://hdl.handle.net/10576/21087
الملخصCarbon nanotubes (CNTs) represent one of the most studied allotropes of carbon. The unique physicochemical properties of CNTs make them among prime candidates for numerous applications in biomedical fields including drug delivery, gene therapy, biosensors, and tissue engineering applications. However, toxicity of CNTs has been a major concern for their use in biomedical applications. In this review, we present an overview of carbon nanotubes in biomedical applications; we particularly focus on various factors and mechanisms affecting their toxicity. We have discussed various parameters including the size, length, agglomeration, and impurities of CNTs that may cause oxidative stress, which is often the main mechanism of CNTs' toxicity. Other toxic pathways are also examined, and possible ways to overcome these challenges have been discussed. 2016 American Chemical Society.
اللغةen
الناشرAmerican Chemical Society
الموضوعCarbon Nanotubes
Biomedical Applications
العنوانCarbon Nanotubes in Biomedical Applications: Factors, Mechanisms, and Remedies of Toxicity
النوعArticle Review
الصفحات8149-8167
رقم العدد18
رقم المجلد59


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