Browsing Academic by Author "Hassan, Arij Fouzat"
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Effects of neratinib on angiogenesis and the early stage of the embryo using chicken embryo as a model.
Kheraldine, Hadeel; Hassan, Arij Fouzat; Alhussein, Hashim; Al-Thawadi, Hamda; Vranic, Semir; Al Moustafa, Ala-Eddin... more authors ... less authors ( the Association of Basic Medical Sciences , 2023 , Article)Angiogenesis is the process of forming new blood capillaries from pre-existing vessels. Even though it is essential during normal development, it plays a major role in cancer progression. Neratinib is a pan-human epidermal ... -
Methanolic Leaves Extract of Ziziphus spina-christi Inhibits Cell Proliferation and Migration of HER2-Positive Breast Cancer via p38 MAPK Signaling Pathway
Saeed, Sumayyah; Hassan, Arij Fouzat; Suliman, Azza; Moustafa, Ala Eddin Al; Alali, Feras ( Multidisciplinary Digital Publishing Institute (MDPI) , 2025 , Article)Human epidermal growth factor receptor 2 (HER2) is a subtype of breast cancer that is associated with poor prognosis and low survival rates. The discovery of novel anti-cancer agents to manage this subtype of cancer is ... -
Neratinib and metformin: A novel therapeutic approach against HER2-Positive Breast Cancer
Kheraldine, Hadeel; Hassan, Arij Fouzat; Saeed, Sumayyah; Merhi, Maysaloun; Mateo, Jericha Miles; Ulamec, Monika; Peric-Balja, Melita; Vranic, Semir; Al-Thawadi, Hamda; Moustafa, Ala-Eddin Al... more authors ... less authors ( Elsevier , 2025 , Article)BackgroundHER2-positive breast cancer (BC) is highly aggressive with a poor prognosis. It is driven by HER2 oncoprotein activation/crosstalk with other receptors like EGFR/(HER1), HER3, and HER4, in addition to IGF-1R, ...