Browsing Academic by Author "Casalbore, Patrizia"
Now showing items 1-4 of 4
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Human olfactory bulb neural stem cells (Hu-OBNSCs) can be loaded with paclitaxel and used to inhibit glioblastoma cell growth
Marei, Hany E.; Casalbore, Patrizia; Althani, Asmaa; Coccè, Valentina; Cenciarelli, Carlo; Alessandri, Giulio; Brini, Anna T.; Parati, Eugenio; Bondiolotti, Gianpietro; Pessina, Augusto... more authors ... less authors ( MDPI , 2019 , Article)Exploitation of the potential ability of human olfactory bulb (hOB) cells to carry, release, and deliver an effective, targeted anticancer therapy within the central nervous system (CNS) milieu remains elusive. Previous ... -
Human Olfactory Bulb Neural Stem Cells Expressing hNGF Restore Cognitive Deficit in Alzheimer's Disease Rat Model
Marei, Hany E.; Farag, Amany; Al-Thani, Asma; Afifi, Nahla; Abd-Elmaksoud, Ahmed; Lashen, Samah; Rezk, Shaymaa; Pallini, Roberto; Casalbore, Patrizia; Cenciarelli, Carlo... more authors ... less authors ( Wiley , 2015 , Article)In this study, we aim to demonstrate the fate of allogenic adult human olfactory bulb neural stem/progenitor cells (OBNSC/NPCs) transplanted into the rat hippocampus treated with ibotenic acid (IBO), a neurotoxicant ... -
The Interference of Notch1 target Hes1 affects cell growth, differentiation and invasiveness of glioblastoma stem cells through modulation of multiple oncogenic targets
Cenciarelli, Carlo; E. Marei, Hany; Zonfrillo, Manuela; Casalbore, Patrizia; Felsani, Armando; Trevisi, Gianluca; Althani, Asma; Mangiola, Annunziato... more authors ... less authors ( Impact Journals , 2017 , Article)The invasive and lethal nature of Glioblastoma multiforme (GBM) necessitates the continuous identification of molecular targets and search of efficacious therapies to inhibit GBM growth. The GBM resistance to chemotherapy ... -
Over-Expression of hNGF in Adult Human Olfactory Bulb Neural Stem Cells Promotes Cell Growth and Oligodendrocytic Differentiation
Marei, Hany E.; Althani, Asmaa; Afifi, Nahla; Abd-Elmaksoud, Ahmed; Bernardini, Camilla; Michetti, Fabrizio; Barba, Marta; Pescatori, Mario; Maira, Giulio; Paldino, Emanuela; Manni, Luigi; Casalbore, Patrizia; Cenciarelli, Carlo... more authors ... less authors ( Public Library of Science ONE Staff , 2013 , Article)The adult human olfactory bulb neural stem/progenitor cells (OBNC/PC) are promising candidate for cell-based therapy for traumatic and neurodegenerative insults. Exogenous application of NGF was suggested as a promising ...