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Na + /H + exchanger isoform 1-induced osteopontin expression facilitates cardiac hypertrophy through p90 ribosomal S6 kinase
( NLM (Medline) , 2018 , Article)Cardiovascular diseases are the leading cause of death worldwide. One in three cases of heart failure is due to dilated cardiomyopathy. The Na+/H+ exchanger isoform 1 (NHE1), a multifunctional protein and the key pH regulator ... -
Na+/H+ exchanger isoform 1 induced cardiomyocyte hypertrophy involves activation of p90 ribosomal S6 Kinase
( Public Library of Science , 2015 , Article)Studies using pharmacological and genetic approaches have shown that increased activity/expression of the Na+/H+ exchanger isoform 1 (NHE1) play a critical role in the pathogenesis of cardiac hypertrophy. Despite the ... -
Na+/H+ exchanger isoform 1 induced osteopontin expression in cardiomyocytes involves NFAT3/Gata4
( Springer-Verlag , 2015 , Article)Osteopontin (OPN), a multifunctional glycophosphoprotein, has been reported to contribute to the development and progression of cardiac remodeling and hypertrophy. Cardiac-specific OPN knockout mice were protected against ... -
Na+/H+ exchanger isoform 1-induced osteopontin expression facilitates cardiomyocyte hypertrophy
( Public Library of Science , 2015 , Article)Enhanced expression and activity of the Na+/H+ exchanger isoform 1 (NHE1) has been implicated in cardiomyocyte hypertrophy in various experimental models. The upregulation of NHE1 was correlated with an increase in osteopontin ... -
Na2FeP2O7 as a Promising Iron-Based Pyrophosphate Cathode for Sodium Rechargeable Batteries: A Combined Experimental and Theoretical Study
( WILEY-VCH Verlag GmbH & Co. , 2013 , Article)Considering the promising electrochemical performance of the recently reported pyrophosphate family in lithium ion batteries as well as the increasing importance of sodium ion batteries (SIBs) for emerging large-scale ... -
Na4MnV(PO4)3-rGO as Advanced cathode for aqueous and non-aqueous sodium ion batteries
( Elsevier B.V. , 2019 , Article)NASICON-type Na4MnV(PO4)3 with reduced graphene oxide (rGO) has been synthesized by the simple sol-gel reaction and characterized by different analytical techniques. The resulted material has been explored as a cathode ... -
Naked Poly(amidoamine) Dendrimer Nanoparticles Exhibit Intrinsic Embryotoxicity During the Early Stages of Normal Development.
( American Science Publishers ASP , 2020 , Article)To investigate the impact of poly(amidoamine) dendrimers (PAMAMs) in the embryo, we explored the outcome of different generations (G₄ and G) on the early stages of embryogenesis using the chicken embryo as a model. We also ... -
Nannobiostrat1graphy Of The Late Cretaceous Paleocene Succession In Esh El-Mallaha Range, Eastern Desert, Egypt
( Qatar University , 1990 , Article)This paper emphasis the biostratigraphic significance of thirty nannofossil species recorded from the Maestrichtian - Paleocene succession in Esh El-Mellaha Range, Eastern Desert, Egypt. These species participated in making ... -
Nano-scale moisture damage evaluation of carbon nanotube-modified asphalt
( Elsevier , 2018 , Article)© 2018 Elsevier Ltd In addition to polymer modification, the use of nanomaterials to improve different asphalt properties has recently been found to be beneficial. However, the potential of nanomaterials in pavement ... -
Nanoclay compatibilization of phase separated polysulfone/polyimide films for oxygen barrier
( Elsevier Ltd , 2017 , Article)Polyimide (PI) and Polysulfone (PSF) films are used in many applications ranging from electronic film capacitors to membranes for gas separation and water purification, yet their phase separation issues limit many potential ... -
Nanocomposite Membranes of Silica and Polysulfone for Improved Gas Permeation
( Elsevier, Ltd , 2012 , Conference Paper)Polysulfone-Silica mixed matrix hybrid membranes have been prepared by incorporating silicon dioxide nanoparticles with average particle size of 136 nm. Two types of polysulfone-silica nanocomposite membranes were prepared ... -
Nanodiagnostics for tuberculosis detection
( Taylor & Francis , 2017 , Article)Introduction Tuberculosis (TB) is a leading killer worldwide. End TB strategy aims at ending the TB epidemic by 2030. Early, accurate, and affordable diagnosis represents a cornerstone to achieve this goal. Innovative ... -
Nanoengineering of Core-Shell Magnetic Mesoporous Microspheres with Tunable Surface Roughness
( American Chemical Society , 2017 , Article)Functional core-shell mesoporous microspheres with integrated functions, controlled structure, and surface properties and morphologies have received increasing attention due to their excellent physicochemical properties. ... -
Nanofibers of resorcinol–formaldehyde for effective adsorption of As (III) ions from mimicked effluents
( Springer Verlag , 2018 , Article)In the present study, the core–shell structured RF/PVA nanofibers have been developed and used for the adsorption of As3+ ions from the mimicked liquid effluents. Efficient-facile fabrication of the structured nanofibers ... -
Nanofibrous alginate membrane coated with cellulose nanowhiskers for water purification
( Springer Verlag , 2018 , Article)The aim of this study was to develop a filtration membrane based on two-layered nanoscale alginate nanofibres reinforced with maize cellulose nanowhiskers (diameter between 3 and 12 nm). Reinforcing of the membrane with ... -
Nanoflower-like Yttrium-doped ZnO Photocatalyst for the Degradation of Methylene Blue Dye
( Blackwell Publishing Inc. , 2018 , Article)Pure ZnO and Yttrium-doped (Y-doped) ZnO at various mol% with flower-like nanostructures are synthesized by a microwave-assisted sol�gel method, followed by investigating the morphologies, crystal structures, optical ... -
Nanomaterial-based biosensors for detection of prostate specific antigen
( Springer-Verlag Wien , 2017 , Article Review)Screening serum for the presence of prostate specific antigen (PSA) belongs to the most common approach for the detection of prostate cancer. This review (with 156 refs.) addresses recent developments in PSA detection based ... -
Nanoparticle-mediated targeted drug delivery for breast cancer treatment
( Elsevier B.V. , 2019 , Article Review)Breast cancer (BC) is the most common malignancy in women worldwide, and one of the deadliest after lung cancer. Currently, standard methods for cancer therapy including BC are surgery followed by chemotherapy or radiotherapy. ... -
Nanopore Sequencing SARS-CoV-2 genome in Qatar
( Qatar University Press , 2020 , Poster)Background: The current pandemic, COVID-19, is cause by an RNA coronavirus that was recently identified as SARS-CoV-2. RNA viruses tend to have a high mutation rate; the rate is around a million times greater than that of ... -
Nanoscale-controlled architecture for the development of ultrasensitive lectin biosensors applicable in glycomics
( Royal Society of Chemistry , 2014 , Article)In this mini-review the most advanced patterning protocols and transducing schemes for the development of ultrasensitive label-free and label-based lectin biosensors for the glycoprofiling of disease markers and some ...
