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Rhus coriaria L. (Sumac) evokes endothelium-dependent vasorelaxation of rat aorta: Involvement of the cAMP and cGMP pathways
(
Frontiers Media S.A.
, 2018 , Article)
Rhus coriaria L. (sumac) is widely used in traditional remedies and cuisine of countries of the Mediterranean as well as Central and South-West Asia. Administration of sumac to experimental models and patients with diverse ...
Anti-atherosclerotic plants which modulate the phenotype of vascular smooth muscle cells
(
Elsevier
, 2016 , Article)
Background: Cardiovascular disease (CVD) remains the leading cause of global death, with atherosclerosis being a major contributor to this mortality. Several mechanisms are implicated in the pathogenesis of this disease. ...
Salinomycin induces apoptosis and senescence in breast cancer: Upregulation of p21, downregulation of survivin and histone H3 and H4 hyperacetylation
(
Elsevier
, 2013 , Article)
Background
In the present study, we investigated the effect of Salinomycin on the survival of three human breast cancer cell lines MCF-7, T47D and MDA-MB-231 grown in adherent culture conditions.
Methods
Cell viability ...
Synthesis of New Chromene Derivatives Targeting Triple-Negative Breast Cancer Cells
(
MDPI
, 2023 , Article)
Breast cancer continues to be the leading cause of cancer-related deaths among women worldwide. The most aggressive type of breast cancer is triple-negative breast cancer (TNBC). Indeed, not only does TNBC not respond well ...
C-peptide in diabetes: A player in a dual hormone disorder?
(
Wiley-Blackwell
, 2024 , Article)
C-peptide, a byproduct of insulin synthesis believed to be biologically inert, is emerging as a multifunctional molecule. C-peptide serves an anti-inflammatory and anti-atherogenic role in type 1 diabetes mellitus (T1DM) ...