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Combined chemo-magnetic field-photothermal breast cancer therapy based on porous magnetite nanospheres
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Nature Research
, 2020 , Article)
The efficacy of different modalities of treating breast cancer is inhibited by several limitations such as off-targeted drug distribution, rapid drug clearance, and drug resistance. To overcome these limitations, we developed ...
Mechanical and durability properties of ultra-high performance steel FRC made with discarded materials
(
Elsevier
, 2021 , Article)
This study investigates the mechanical and durability properties of 12 ultra-high performance fiber reinforced concrete (UHPFRC) mixes manufactured using alternate aggregate sources. Natural gabbro aggregates (GA), steel ...
Biased signaling: A viable strategy to drug ghrelin receptors for the treatment of obesity
(
Elsevier
, 2021 , Article)
Obesity is a global burden and a chronic ailment with damaging overall health effects. Ghrelin, an octanoylated 28 amino acid peptide hormone, is secreted from the oxyntic mucosa of the stomach. Ghrelin acts on regions of ...
Structure-Based Virtual Screening to Identify Novel Potential Compound as an Alternative to Remdesivir to Overcome the RdRp Protein Mutations in SARS-CoV-2.
(
Frontiers Media
, 2021 , Article)
The number of confirmed COVID-19 cases is rapidly increasing with no direct treatment for the disease. Few repurposed drugs, such as Remdesivir, Chloroquine, Hydroxychloroquine, Lopinavir, and Ritonavir, are being tested ...
Missing and unerupted teeth in osteogenesis imperfecta
(
Elsevier
, 2021 , Article)
IntroductionOsteogenesis imperfecta (OI) is a genetic disorder characterized by bone fragility and craniofacial and dental abnormalities such as congenitally missing teeth and teeth that failed to erupt which are believed ...
Two new sponge species (Demospongiae: Chalinidae and Suberitidae) isolated from hyperarid mangroves of Qatar with notes on their potential antibacterial bioactivity.
(
Public Library of Science
, 2020 , Article)
This study presents the taxonomic description of two new sponge species that are intimately associated with the hyperarid mangrove ecosystem of Qatar. The study includes a preliminary evaluation of the sponges' potential ...
Mental distress and its associations with behavioral outcomes during the COVID-19 pandemic: a national survey of Chinese adults
(
Elsevier
, 2021 , Article)
ObjectivesThis study aimed to evaluate associations between mental distress and COVID-19-related changes in behavioral outcomes and potential modifiers (age, gender, educational attainment) of such associations. Study ...
Association of Complement-Related Proteins in Subjects With and Without Second Trimester Gestational Diabetes.
(
Frontiers Media
, 2021 , Article)
Gestational Diabetes Mellitus (GDM) development is related to underlying metabolic syndrome that is associated with elevated complement C3 and C4. Elevated C3 levels have been associated with preeclampsia and the development ...
Sestrin2 suppression aggravates oxidative stress and apoptosis in endothelial cells subjected to pharmacologically induced endoplasmic reticulum stress
(
Elsevier
, 2021 , Article)
Endoplasmic reticulum (ER) stress is an inflammatory response that contributes to endothelial dysfunction, a hallmark of cardiovascular diseases, in close interplay with oxidative stress. Recently, Sestrin2 (SESN2) emerged ...
Historical Criticism and Recent Trends in Western Scholarship on the Qur’an: Some Hermeneutic Reflections
(
Qatar University Press
, 2020 , Article)
The application of the historical-critical method to the Qur’an is sometimes viewed as an imperialist attempt to undermine Islamic belief. This view, however, fails to sufficiently consider that the same method has also ...