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Metabolic GWAS of elite athletes reveals novel genetically-influenced metabolites associated with athletic performance.
(
Nature Research
, 2019 , Article)
Genetic research of elite athletic performance has been hindered by the complex phenotype and the relatively small effect size of the identified genetic variants. The aims of this study were to identify genetic predisposition ...
Encoding the β-Arrestin Trafficking Fate of Ghrelin Receptor GHSR1a: C-Tail-Independent Molecular Determinants in GPCRs
(
American Chemical Society
, 2019 , Article)
G-protein-coupled receptors (GPCRs) can bias signaling through distinct biochemical pathways that originate from G-protein/receptor and β-arrestin/receptor complexes. Receptor conformations supporting β-arrestin engagement ...
Co2+ substituted for Bi3+ in BiVO4 and its enhanced photocatalytic activity under visible LED light irradiation
(
Royal Society of Chemistry
, 2019 , Article)
We investigated the fabrication of Co-doped BiVO4 (Bi1-xCoxVO4+δ, 0.05 < x < 0.5) by the substitution of Co ions for Bi sites in BiVO4. The X-ray diffraction (XRD), Raman, and X-ray photoelectron spectroscopy (XPS) results ...
SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs
(
Taylor and Francis Ltd.
, 2019 , Article)
The present study describes the synthesis of a series of 22 chalcone analogs. These compounds were evaluated as potential human MAO-A and MAO-B inhibitors. The compounds showed varied selectivity against the two isoforms. ...
Drug-free holidays: Compliance, tolerability, and acceptability of a 3-day atovaquone/proguanil schedule for pretravel malaria chemoprophylaxis in australian travelers
(
Oxford University Press
, 2019 , Article)
Background
Poor compliance with chemoprophylaxis is a major contributing factor to the risk of malaria in travelers. Pre-travel chemoprophylaxis may improve compliance by enabling “drug-free holidays.” The standard treatment ...
Electrically conductive, transparent polymeric nanocomposites modified by 2D Ti3C2Tx (MXene)
(
MDPI AG
, 2019 , Article)
The electrically conductive, transparent, and flexible self-standing thin nanocomposite films based on copolyamide matrix (coPA:Vestamelt X1010) modified with 2D Ti3C2Tx (MXene) nanosheets were prepared by casting and their ...
Postprandial insulin and triglyceride concentrations are suppressed in response to breaking up prolonged sitting in Qatari females
(
Frontiers Media S.A.
, 2019 , Article)
Background: Cultural, environmental and logistical factors challenge the Qatari population, particularly females, to engage in physical activity, and there is a high prevalence of diabetes in this population. Sedentary ...
Some Majorization Integral Inequalities for Functions Defined on Rectangles Via Strong Convexity
(
Ilirias Research Institute
, 2019 , Article)
In this paper, we have extended some integral majorization types and generalized Favard’s inequalities from functions defined on intervals to functions defined on rectangles via strong convexity and apply the results to ...
Exploring the gaps between education and pharmacy practice on antimicrobial stewardship: a qualitative study among pharmacists in Qatar.
(
Taylor & Francis Group
, 2019 , Article)
Antimicrobial resistance is a public health issue and is the focus of antimicrobial stewardship (AMS) teams within health care institutions. However, AMS is not comprehensively and fully taught in medical or pharmacy ...
Is age of menarche among school girls related to academic performance
(
De Gruyter
, 2019 , Article)
There is strong evidence that the mean age of menarche has declined over the last few decades in developed and developing countries. This is of a major concern because of its enormous public health implications. This study ...